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个人简介
Our research focuses on developing single-cell and single-molecule imaging approaches to improve our understanding of stem cell renewal and differentiation.
In particular, we are interested in how chromatin binding proteins regulate genome architecture and gene expression during stem cell fate transitions and why they are often misregulated during early cancer progression. Single-cell approaches are key to understand how these proteins work due to the considerable cell heterogeneity that occurs during stem cell fate transitions.
In particular, we are interested in how chromatin binding proteins regulate genome architecture and gene expression during stem cell fate transitions and why they are often misregulated during early cancer progression. Single-cell approaches are key to understand how these proteins work due to the considerable cell heterogeneity that occurs during stem cell fate transitions.
研究兴趣
论文共 36 篇作者统计合作学者相似作者
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Marissa E. Nolan,Victoria Aranda, Sangjun Lee, Balasubramanian Lakshmi,Srinjan Basu,D. Craig Allred,Senthil K. Muthuswamy
crossref(2023)
Marissa E. Nolan,Victoria Aranda, Sangjun Lee, Balasubramanian Lakshmi,Srinjan Basu,D. Craig Allred,Senthil K. Muthuswamy
crossref(2023)
Maike Steindel, Igor Orsine de Almeida,Stanley Strawbridge, Valentyna Chernova,David Holcman,Aleks Ponjavic,Srinjan Basu
bioRxiv (Cold Spring Harbor Laboratory) (2022)
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biorxiv(2022)
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