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职业迁徙
个人简介
At Hunter College he teaches courses in polymer chemistry and environmental science and technology and conducts research centered around polymers.
RESEARCH STATEMENT
The Alexandratos Lab approaches radiochemistry from the standpoint of separations and of sensors.
*Ionic Crystals: Synthesis of modified structures and their study for environmental remediation* Ionic crystals are a class of inorganic polymers. With them, we are developing a new class of biocompatible inorganic /organic hybrid structures via green chemistry utilizing interfacial reactions. The building blocks for these coordination polymers are an ionic crystal, a modifier with an organic anion having a high affinity for the crystal’s cation, and substituents on the modifier which can change the hybrid’s polarity.
Generally, the ionic crystal M+X- is reacted with a modifier A+B- and, in an ion exchange reaction, M+ binds B- to yield a net solid-to-solid conversion. Examples of each component are hydroxyapatite (HAP, Ca10(PO4)6(OH)2), hydroxyethane-1,1-diphosphonate (HEDP), and alendronate (XDP). The polarity of the crystal can be varied further by incorporating transition and lanthanide metal ions.
The hybrids are subjected to characterization by a number of techniques, including FTIR, solid state NMR, electron microscopy, and X-ray diffraction. This research impacts environmental remediation, drug delivery, and valorization. First results with adsorption isotherms on a hybrid show it to have a high affinity for a dye, making it competitive with organic polymers: Modification of HAP with HEDP in the equation shown increases its affinity for methylene blue, a toxic dye contaminant in water from 10 mg MB /g HAP to 893 mg MB / g.
Since dyes are pollutants in rivers and other water supplies, the high capacity allows application to environmental remediation. That it is biocompatible gives it an important advantage over organic polymers. Biocompatibility combined with high capacity makes the modified HAP attractive for drug delivery applications.
Results with the dye imply high loading is possible with antibiotics. The modified HAP can be implanted and slowly release the antibiotic into the body. In terms of valorization, natural HAP derives from animal bones and other sources regarded as waste; We render this waste useful (i.e., valorize) by using it as a reactant in the modification reaction.
RESEARCH STATEMENT
The Alexandratos Lab approaches radiochemistry from the standpoint of separations and of sensors.
*Ionic Crystals: Synthesis of modified structures and their study for environmental remediation* Ionic crystals are a class of inorganic polymers. With them, we are developing a new class of biocompatible inorganic /organic hybrid structures via green chemistry utilizing interfacial reactions. The building blocks for these coordination polymers are an ionic crystal, a modifier with an organic anion having a high affinity for the crystal’s cation, and substituents on the modifier which can change the hybrid’s polarity.
Generally, the ionic crystal M+X- is reacted with a modifier A+B- and, in an ion exchange reaction, M+ binds B- to yield a net solid-to-solid conversion. Examples of each component are hydroxyapatite (HAP, Ca10(PO4)6(OH)2), hydroxyethane-1,1-diphosphonate (HEDP), and alendronate (XDP). The polarity of the crystal can be varied further by incorporating transition and lanthanide metal ions.
The hybrids are subjected to characterization by a number of techniques, including FTIR, solid state NMR, electron microscopy, and X-ray diffraction. This research impacts environmental remediation, drug delivery, and valorization. First results with adsorption isotherms on a hybrid show it to have a high affinity for a dye, making it competitive with organic polymers: Modification of HAP with HEDP in the equation shown increases its affinity for methylene blue, a toxic dye contaminant in water from 10 mg MB /g HAP to 893 mg MB / g.
Since dyes are pollutants in rivers and other water supplies, the high capacity allows application to environmental remediation. That it is biocompatible gives it an important advantage over organic polymers. Biocompatibility combined with high capacity makes the modified HAP attractive for drug delivery applications.
Results with the dye imply high loading is possible with antibiotics. The modified HAP can be implanted and slowly release the antibiotic into the body. In terms of valorization, natural HAP derives from animal bones and other sources regarded as waste; We render this waste useful (i.e., valorize) by using it as a reactant in the modification reaction.
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Jafar Sunga Ali, Tanja Tane, Dihara Hossain,Jasmine Wang,Samuel Groveman,Jacopo Samson,Fatima Kabalan,Sandrine Huclier-Markai,Akira Kawamura,Spiro D. Alexandratos,Ali Younes
Jafar Sunga Ali, Michelle Ma, Malika Alamova, Chloe Chong,Artem Duda, Felicity Liu,Samuel Groveman,Spiro D Alexandratos,Ali Younes
Chemical research in toxicologyno. 11 (2023): 1693-1702
Ali Younes,Jafar Ali,Mohamed Tousif Nur,Artem Duda,Jasmine Wang,Jacopo Samson,Akira Kawamura,Lynn Francesconi,Spiro Alexandratos, Charles Micheal Drain
semanticscholar(2020)
Ali Younes,Jafar Sunga Ali, Mohamed Tousif Nur,Artem Duda,Jasmine Wang, Jacopo Samson,Akira Kawamura, Lynn Francesconi,Spiro Alexandratos,Charles Michael Drain
Spiro D. Alexandratos, Naty Barak, Diana Bauer,F. Todd Davidson,Brian R. Gibney,Susan S. Hubbard, Hessy L. Taft,Paul Westerhof
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