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Bio
Sophie Lelièvre, D.V.M., Ph.D., LL.M.P.H.
Dir. Prevention program REGEN (Relations Genes-Environment) and laboratory of Sensibility of Cancers to Treatments (SCaT)
Sophie Lelièvre is Professor Emerita of Cancer Pharmacology at Purdue University (USA) where she was a Professor for 20 years before joining the Institut de Cancérologie de l’Ouest/Integrated Center for Oncology (ICO) in March 2021. She was trained as a veterinarian before entering the world of cancer research at the Gustave Roussy Institute (Villejuif) during her PhD in molecular and cellular pharmacology from the University Pierre & Marie Curie (Paris 6).
She joined Purdue University as a faculty member in 2000, in the department of Basic Medical Sciences, after a postdoctoral tenure in the laboratory of Mina J. Bissell, a leader in extracellular matrix signaling and breast cancer research, in Berkeley, California. In 2008, Sophie Lelièvre was appointed Associate Director for Scientific Collaborations of the Purdue Center for Cancer Research, then in 2017, co-leader of the Molecular Therapy and Detection Program. In addition to her research laboratory focused on the functional organization of the cell nucleus in differentiation and cancer, she created in 2015 a service laboratory in the Birck Nanotechnology Center of Purdue Discovery Park aimed at developing in vitro research models based on human tissue engineering. The creation of this service laboratory was spurred by her extended knowledge of 3D cell culture not only for tumor models but also for models of normal tissue differentiation that are necessary when working on the mechanisms of cancer risk. Sophie Lelièvre's research work was illustrated several times in reports to the U.S. Congress, which funds medical research programs.
At the ICO, Sophie Lelièvre is Director of the Prevention Program 'Gene-Environment Relationships - REGEN' and of the Laboratory 'Sensitivity of Cancers to Treatments - SCAT'. The REGEN program is based on the scientific approach led by the International Breast Cancer & Nutrition (IBCN) Network, which she created in 2010. The goal of the IBCN network is to conduct transdisciplinary projects on primary prevention of cancer by focusing on the environment, community health and the epigenome. The IBCN is endorsed by the World Health Organization and has a mission of research, communication and training in cancer prevention.
Research Interests
Papers共 125 篇Author StatisticsCo-AuthorSimilar Experts
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JOURNAL OF CELL SCIENCEno. 5 (2024)
crossref(2023)
Journal of cell scienceno. 5 (2023)
ACS biomaterials science & engineeringno. 3 (2023): 1620-1628
NAR cancerno. 4 (2021): zcab043-zcab043
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