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个人简介
Soo-Kyung Lee’s long-term goals are to dissect gene regulatory events that lead to the cellular diversity and eventually formation of functional neural circuits in the CNS and to understand genetic and mechanistic basis for neurodevelopmental defects, ultimately contributing to the generation of better treatment strategies for human developmental disorders.
Over the past decade, Lee has pioneered biochemical and molecular approaches in mouse and chick embryos to unravel the fundamental principles controlling gene expression and cell fate specification in the developing CNS. This led to a series of seminal discoveries into the gene regulatory network required for neuronal fate specification.
More recently, Lee has begun dissecting a human autism disorder FoxG1 syndrome, characterized by severe deficits in cortex development along with other life-threatening symptoms. Soo is devoted to understanding the FoxG1 biology and also engaged in translational research to find a cure for the disorder.
研究兴趣
论文共 74 篇作者统计合作学者相似作者
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Shin Jeon, Jaein Park, Shibi Likhite, Ji Hwan Moon, Dongjun Shin, Liwen Li, Kathrin C. Meyer, Jae W. Lee,Soo-Kyung Lee
Molecular Therapy: Methods & Clinical Developmentno. 3 (2024): 101275
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Estelle Renaux, Charlotte Baudouin, Damien Marchese, Yoanne Clovis,Soo-Kyung Lee, Françoise Gofflot, René Rezsohazy,Frédéric Clotman
Cellular and Molecular Life Sciencesno. 1 (2024): 1-17
Jaein Park,Ji Hwan Moon, Holly O'Shea, Dongjun Shin, Seon Ung Hwang, Liwen Li,Hyojong Lee,Elise Brimble, Jae Lee, Stewart Clark,Soo-Kyung Lee,Shin Jeon
Research square (2023)
Janghyun Kim,Bora Lee,Dae-Hwan Kim, Jae Gwang Yeon,Jeongkyung Lee, Younjung Park, Yuna Lee,Soo-Kyung Lee,Seunghee Lee, Jae W Lee
Christian Huisman,Hyeyoung Cho,Olivier Brock,Su Jeong Lim,Sung Min Youn, Younjung Park,Sangsoo Kim,Soo-Kyung Lee,Alessio Delogu, Jae W. Lee
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