基本信息
views: 2
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
Current projects in the Nair Laboratory:
1] Dendritic cell vaccines using tumor-antigen encoding RNA (mRNA, total tumor RNA, amplified tumor mRNA)
2] Local immune receptor modulation using mRNA that encodes for antibodies, receptor-ligands, cytokines, chemokines and toll-like receptors (current target list: CTLA4, GITR, PD1, TIM3, LAG3, OX40 and 41BB)
3] Combination therapies for cancer: cytotoxic therapy (radiation, chemo and oncolytic poliovirus therapy) with dendritic cell-based vaccines and immune checkpoint blockade
4] Adoptive T cell therapy using tumor RNA-transfected dendritic cells to expand tumor-specific T cells ex vivo
5] Adoptive T cell therapy using PSMA CAR (chimeric antigen receptor) RNA-transfected T cells
6] Direct injection of tumor antigen encoding RNA (targeting antigens to dendric cells in vivo using nanoparticles and aptamers)
1] Dendritic cell vaccines using tumor-antigen encoding RNA (mRNA, total tumor RNA, amplified tumor mRNA)
2] Local immune receptor modulation using mRNA that encodes for antibodies, receptor-ligands, cytokines, chemokines and toll-like receptors (current target list: CTLA4, GITR, PD1, TIM3, LAG3, OX40 and 41BB)
3] Combination therapies for cancer: cytotoxic therapy (radiation, chemo and oncolytic poliovirus therapy) with dendritic cell-based vaccines and immune checkpoint blockade
4] Adoptive T cell therapy using tumor RNA-transfected dendritic cells to expand tumor-specific T cells ex vivo
5] Adoptive T cell therapy using PSMA CAR (chimeric antigen receptor) RNA-transfected T cells
6] Direct injection of tumor antigen encoding RNA (targeting antigens to dendric cells in vivo using nanoparticles and aptamers)
Research Interests
Papers共 36 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
ANNALS OF SURGICAL ONCOLOGYno. 1 (2024): S65-S65
Cited0Views0Bibtex
0
0
bioRxiv : the preprint server for biologyno. Suppl 1 (2023)
crossref(2023)
Sean R. McCutcheon,Adam M. Swartz, Michael C. Brown,Alejandro Barrera,Christian McRoberts Amador,Keith Siklenka,Lucas Humayun, Maria A. ter Weele,James M. Isaacs,Timothy E. Reddy,Andrew S. Allen,Smita K. Nair,
Nature geneticsno. 12 (2023): 2211-+
crossref(2023)
Neuro-oncologyno. Supplement_5 (2023): v143-v143
openalex(2023)
crossref(2023)
crossref(2023)
Sean R. McCutcheon,Adam M. Swartz, Michael C. Brown,Alejandro Barrera,Christian McRoberts Amador,Keith Siklenka,Lucas Humayun, Maria A. ter Weele, Andrea R Daniel,Timothy E. Reddy,Andrew S. Allen,Smita K. Nair,
crossref(2023)
Load More
Author Statistics
#Papers: 36
#Citation: 519
H-Index: 7
G-Index: 18
Sociability: 5
Diversity: 2
Activity: 38
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn