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Bio
Currently, I am working on adeno-associated virus(AAV) based gene therapy. AAV is a member of Parvoviridae, and it is a single-stranded DNA virus with an icosahedral capsid about 23 nm in diameter. My project is focusing on how to improve the transfection efficiency via modulating viral capsid protein sequence structure and identifying the critical host cell receptors as well as intracellular transfection factors. By doing these, I expect to increase the AAV transfection efficiency to overcome the high viral titer required on gene therapies.
Besides, I also work in the BSL3 lab to investigate the long-term infection pattern of SARS-COV2. I found that the viral infection is persisting, and virion released from the airway epithelial is tending to be recurrent. Further, I am trying to identify the damage pathways during the SARS-CoV-2 infection.
Research Interests
Papers共 24 篇Author StatisticsCo-AuthorSimilar Experts
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Journal of virologyno. 6 (2024): e0063324-e0063324
MOLECULAR THERAPYno. 4 (2023): 226-226
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bioRxiv : the preprint server for biology (2023)
Molecular therapy. Methods & clinical development (2023): 101115-101115
Research squareno. 7 (2023): 2019-2019
MOLECULAR THERAPYno. 4 (2023): 566-567
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Journal of virologyno. 12 (2023): e0133023-e0133023
MOLECULAR THERAPYno. 4 (2023): 7-7
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Author Statistics
#Papers: 22
#Citation: 218
H-Index: 7
G-Index: 14
Sociability: 4
Diversity: 0
Activity: 0
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