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个人简介
Dr. Adham is an Associate Professor of Molecular Cancer Biology, Sultan Qaboos University, Muscat, Oman. Dr. Adham's research has focused on two gynecological related cancers, Ovarian and breast cancer. Earlier, Dr. Adham was able to validate the role of angiogenesis-related molecule vascular endothelial growth factor (VEGF) in epithelial ovarian cancer (EOC), she discovered a VEGF-A/KDR dependent autocrine loop to inhibit “anoikis” a type of cell death triggered due to cells detachment from the extracellular matrix. Later, through translational studies, Dr. Adham found a new role for the glycoprotein Neuropilin-1 in enhancing the epithelial to mesenchymal transition (EMT) pathway in ovarian cancer. More recently, she discovered the mechanism and association between Neuropilin-1 and HER-2 proteins and their role to induce chemotherapy resistance in breast cancer cells.
研究兴趣
论文共 42 篇作者统计合作学者相似作者
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FRONTIERS IN ONCOLOGY (2022): 1100427-1100427
Moleculesno. 14 (2021): 4240
Resistance to Targeted Anti-Cancer TherapeuticsCurrent Applications for Overcoming Resistance to Targeted Therapiespp.131-159, (2019)
Noura Al-Zeheimi,Adviti Naik,Charles Saki Bakheit,Marwa Al Riyami, Adil Al Ajarrah, Suaad Al Badi,Khalid Al Baimani, Kamran Malik, Zamzam Al Habsi,Mansour S Al Moundhri,Sirin A Adham
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作者统计
#Papers: 42
#Citation: 805
H-Index: 19
G-Index: 28
Sociability: 5
Diversity: 0
Activity: 0
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