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个人简介
Prof. Sima Lev is an expert in cell signaling and membrane trafficking. Her current studies focus on breast cancer signaling and metastasis. Over the last 20 years her research ranged across: (1) different aspects of membrane trafficking, in particular regulatory mechanisms of intracellular lipid transport and vesicular fusion, (2) Phosphatidylinositol (PI)-transfer proteins and their role in phosphoinositide signaling, (3) Signaling by the non-receptor tyrosine kinase PYK2 in cancer cells, (4) Regulatory mechanisms of triple negative breast cancer (TNBC) progression and metastasis, and (5) identification of therapeutic targets and combination therapies for different molecular subtypes of TNBC.
Her pioneer studies provide novel mechanistic insights into the field of membrane trafficking and cell signaling in cancer biology. Prof. Lev discovered the non-receptor tyrosine kinase PYK2 and then isolated a family of lipid transfer proteins designated Nir1, Nir2, and Nir3.
Her pioneer studies provide novel mechanistic insights into the field of membrane trafficking and cell signaling in cancer biology. Prof. Lev discovered the non-receptor tyrosine kinase PYK2 and then isolated a family of lipid transfer proteins designated Nir1, Nir2, and Nir3.
研究兴趣
论文共 103 篇作者统计合作学者相似作者
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Yaron Vinik, Avi Maimon,Vinay Dubey,Harsha Raj,Ifat Abramovitch,Sergey Malitsky,Maxim Itkin, Avi Ma'ayan,Frank Westermann,Eyal Gottlieb,Eytan Ruppin,Sima Lev
A. Massarwa,T. Weissbach,T. Elkan Miller, L. Adamo, S. Czeiger,S. Lev,A. Weissmann‐Brenner,B. Weisz,Y. Yinon,E. Hadi,E. Kassif
Ultrasound in obstetrics & gynecologyno. S1 (2021): 180-180
Social Science Research Network (2021)
Advanced science (Weinheim, Baden-Wurttemberg, Germany)no. 3 (2021): 2003049-2003049
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#Papers: 103
#Citation: 9422
H-Index: 44
G-Index: 78
Sociability: 6
Diversity: 3
Activity: 25
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