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Dr. Veasey’s laboratory focuses on identifying the molecular mechanisms underlying neural injury in sleep disorders and sleep disruption. The present focus of her lab is understanding the molecular mechanisms by which sleep disruption injures and even kills select neurons. Previously sleep researchers believed that all neurobehavioral consequences of sleep loss were fully reversible. Dr. Veasey's lab has led the way in discovering that chronic short sleep and sleep fragmentation induce loss of wake-activated neurons, neurons essential for alertness and optimal cognitive performance. Most recently her lab has discovered that chronic sleep loss incites an amyloid cascade within locus coeruleus neurons and that this cascade leads to an unstoppable progression of tau degeneration marching throughout the forebrain.
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Translational Medicine Research Sleep and its Disorderspp.209-226, (2022)
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