基本信息
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Career Trajectory
Bio
Our research focuses on algorithm development and integrative mining from high-throughput data to understand gene regulation in cancer biology. We have developed a number of widely used algorithms for transcription factor motif finding, ChIP-chip / ChIP-seq / DNase-seq / CRISPR Screen data analysis. Through integrating genome-wide transcription factor binding, chromatin dynamics, gene expression profiles, and chemical and functional screens, we try to model the specificity and function of transcription factors, chromatin regulators, RNA binding proteins, kinases, and lncRNAs in tumor development, progression, drug response and resistance.
Research Interests
Papers共 384 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
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期刊级别
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合作机构
Cancer Researchno. 6_Supplement (2024): 1523-1523
X. Shirley Liu, Yulong Li, Xiangyang Wu,Hailing Liu,Huizhu Liu,Caibin Sheng,Qingyang Ding, Yixuan Tang, Chao Liu, Bin Xie, Xi Xiao, Quan Yu,
Cancer Researchno. 6_Supplement (2024): 3914-3914
crossref(2023)
Nature Communicationsno. 1 (2023): 1-12
crossref(2023)
crossref(2023)
Christina V Theodoris,Ling Xiao,Anant Chopra,Mark D Chaffin,Zeina R Al Sayed,Matthew C Hill, Helene Mantineo, Elizabeth M Brydon,Zexian Zeng,X Shirley Liu,Patrick T Ellinor
Natureno. 7965 (2023): 616-624
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Author Statistics
#Papers: 387
#Citation: 94467
H-Index: 122
G-Index: 291
Sociability: 8
Diversity: 3
Activity: 355
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