基本信息
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Career Trajectory
Bio
Graduate School of Pharmaceutical Sciences, Kyoto University (April 1998 – March 2003) Sakyo-ku, Kyoto 606-8501, Japan。 Faculty of Pharmaceutical Sciences, Kyoto University Sakyo-ku, Kyoto 606-8501, Japan。
Senior Lecturer (June 2009 – present)。 Assistant Professor (January 2006 – May 2009)。 Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan。 Senior Lecturer (June 2004 – December 2005) Graduate School of Pharmaceutical Sciences, University of Shizuoka Suruga-ku, Shizuoka 422-8526, Japan。 JSPS Postdoctoral Fellow for Research Abroad / Visiting Fellow (April 2003 – May 2004)。 Laboratory of Medicinal Chemistry, National Cancer Institute, NIH, US。 JSPS Research Fellow (April 2001 – May 2003) Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan。
DEGREES and AWARDS:
Ph.D., Pharmaceutical Sciences, March 2003 (Prof. Nobutaka Fujii)
Master of Pharmaceutical Sciences, March 2003 (Prof. Nobutaka Fujii)
Bachelor of Pharmaceutical Sciences, March 1998
The Pharmaceutical Society of Japan Award for Young Scientists (March 2009)
Kinki Branch Award for Encouragement of Research, the Pharmaceutical Society of Japan (January 2003)
PUBLICATIONS
1 Yoshimitsu, Y.; Oishi, S.; Miyagaki, J.; Inuki, S.; Ohno, H.; Fujii, N. Pachastrissamine (jaspine B) and its
stereoisomers inhibit sphingosine kinases and atypical protein kinase C. Bioorg. Med. Chem. 2011, 19(18)
5402-5408.
2 Takeuchi, T.; Oishi, S.; Watanabe, T.; Ohno, H.; Sawada, J.; Matsuno, K.; Asai, A.; Asada, N.; Kitaura, K.;
Fujii, N. Structure–activity relationships of carboline and carbazole derivatives as a novel class of ATPcompetitive
kinesin spindle protein inhibitors. J. Med. Chem. 2011, 54(13) 4839-4846.
3 Inokuchi, E.; Oishi, S.; Kubo, T.; Ohno, H.; Shimura, K.; Matsuoka, M.; Fujii, N. Potent CXCR4 antagonists
containing amidine-type peptide bond isosteres. ACS Med. Chem. Lett. 2011, 2(6) 477-480.
4 Masuda, R.; Oishi, S.; Ohno, H.; Kimura, H.; Saji, H.; Fujii, N. Concise site-specific synthesis of DTPApeptide
conjugates: application to imaging probes for the chemokine receptor CXCR4. Bioorg. Med. Chem.
2011, 19(10) 3216-3220.
5 Oishi, S.; Misu, R.; Tomita, K.; Setsuda, S.; Masuda, R.; Ohno, H.; Naniwa, Y.; Ieda, N.; Inoue, N.; Ohkura,
S.; Uenoyama, Y.; Tsukamura, H.; Maeda, K.; Hirasawa, A.; Tsujimoto, G.; Fujii, N. Activation of
neuropeptide FF receptors by kisspeptin receptor ligands. ACS Med. Chem. Lett. 2011, 2(1) 53-57.
6 Oishi, S.; Watanabe,K.; Ito, S.; Ta naka, M.; Nishikawa, H.; Ohno, H.; Shimane, K.; Izumi, K.; Sakagami, Y.;
Kodama, E. N.; Matsuoka, M.; Asai, A.; Fujii, N. Affinity selection and sequence-activity relationships of
HIV-1 membrane fusion inhibitors directed at the drug-resistant variants. Med. Chem. Commun. 2010, 1(4)
276-281.
7 Oishi, S.; Watanabe, T.; Sawada, J.; Asai, A.; Ohno, H.; Fujii, N. Kinesin spindle protein (KSP) inhibitors
with 2,3-fused indole scaffolds. J. Med. Chem. 2010, 53(13) 5054-5058.
8 Narumi, T.; Hayashi, R.; Tomita, K.; Kobayashi, K.; Tanahara, N.; Ohno, H.; Naito, T.; Kodama, E.;
Matsuoka, M.; Oishi, S.; Fujii, N. Synthesis and biological evaluation of selective CXCR4 antagonists
containing alkene dipeptide isosteres. Org. Biomol. Chem. 2010, 8(3) 616-621.
9 Kajiwara, K.; Watanabe, K.; Tokiwa, R.; Kurose, T.; Ohno, H.; Tsutsumi, H.; Hata, Y.; Izumi, K.; Kodama,
E.; Matsuoka, M.; Oishi, S.; Fujii, N. Bioorganic synthesis of a recombinant HIV-1 fusion inhibitor, SC35EK,
with an N-terminal pyroglutamate capping group. Bioorg. Med. Chem. 2009, 17(23) 7964-7970.
10 Tanaka, M.; Kajiwara, K.; Tokiwa, R.; Watanabe, K.; Ohno, H.; Tsutsumi, H.; Hata, Y.; Izumi, K.; Kodama,
E.; Matsuoka, M.; Oishi, S.; Fujii, N. Bioorganic synthesis of end-capped anti-HIV peptides by simultaneous
cyanocysteine-mediated cleavages of recombinant proteins. Bioorg. Med. Chem. 2009, 17(21) 7487-7492.
Research Interests
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INTERNATIONAL SYMPOSIUM ON INTERFACIAL JOINING AND SURFACE TECHNOLOGY (IJST2013) (2014)
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