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个人简介
My research focuses on multiple aspects of regenerative medicine including identification of new sources of cells and scaffolds for tissue engineering, tissue neovascularization, real-time imaging technologies and fabrication of bioengineered tissues as developmental and disease models. Specific examples are the use of tissue-derived extracellular matrices as scaffolds for whole organ bioengineering.
My lab has published a seminal manuscript describing, for the first time, the making of functional small human livers from liver progenitor cells. Using a similar approach, my lab developed small, 3D tissue constructs (organoids) for testing of new drugs without the need to tests in animals. We used the organoids to study human organogenesis in vitro and disease modeling, including tissue fibrosis and cancer. This technology will allow to develop new drugs to treat many diseases and test them on cells derived from individual patients.
My lab has published a seminal manuscript describing, for the first time, the making of functional small human livers from liver progenitor cells. Using a similar approach, my lab developed small, 3D tissue constructs (organoids) for testing of new drugs without the need to tests in animals. We used the organoids to study human organogenesis in vitro and disease modeling, including tissue fibrosis and cancer. This technology will allow to develop new drugs to treat many diseases and test them on cells derived from individual patients.
研究兴趣
论文共 440 篇作者统计合作学者相似作者
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CURRENT OPINION IN BIOMEDICAL ENGINEERING (2024): 100531
Annals of Surgical Oncologyno. 8 (2024): 1-13
Cecilia R. Schaaf, Tiefu Liu, Damian Hutchins,Mitra Kooshki, Calvin Wagner, Nicholas Edenhoffer,Steven Forsythe, Robyn Greissinger,Lance Miller,Pierre Triozzi,Edward Levine,Shay Soker,
Cancer Researchno. 6_Supplement (2024): 19-19
JunTae Huh, Joao Paulo R L L Parra,Joshua S Copus,Hyun-Wook Kang,Colin E Bishop,Shay Soker,Sean Murphy,Thomas D Shupe,James J Yoo,Sang Jin Lee,Anthony Atala
Tissue engineering. Part Ano. 13-14 (2024): 333-341
CANCERSno. 24 (2023)
Cancer Researchno. 7_Supplement (2023): 164-164
Cancer Researchno. 7_Supplement (2023): 6043-6043
ANNALS OF SURGICAL ONCOLOGYno. SUPPL 1 (2023): S48-S49
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Science translational medicineno. 716 (2023): eadf7547-eadf7547
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