Dr. Zhang's research is on the interface of medical imaging informatics, computer vision and machine learning. His work related to robust and large-scale medical image analytics has earned several awards, including multiple Young Scientist Awards and finalists in MICCAI, one of the most cited articles in Medical Image Analysis, and the Ralph E. Powe Junior Faculty Enhancement Award from Oak Ridge Associated Universities. Dr. Zhang has been (co)advising amazing students, who have received the Best Paper Travel Award in ISBI 2014 (3 out of 600) and its finalist in ISBI 2015, by Xiaofan Zhang; the Young Scientist Award in MICCAI 2015 (4 out of 810), by Menglin Jiang; and the Front Cover Article in Medical Physics, May 2013, by Guotai Wang. Dr. Zhang's research was funded by multiple NSFs (ABI, CRI-II, I/UCRC) and industrial collaborators. He is on the editorial board of Neurocomputing and a senior member of the IEEE.