His research focused on the structure and function of the presenilin homologue (PSH), which provided valuable insights into gamma-secretase and Alzheimer’s disease.He worked in the lab of Professor Yifan Cheng, supported by a Human Frontier Science Program (HFSP) Long-term fellowship. During his postdoc training, he received comprehensive training in cryo-electron microscopy (cryo-EM) and successfully determined the structures of several membrane proteins, including TMEM16 and TRP family proteins, using the single-particle cryo-EM technique