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Seychelle M. Vos investigates how genome organization and gene expression are physically coupled across molecular scales.
We study the interplay of gene expression and genome organization. Our work focuses on understanding how large molecular machineries involved in genome organization and gene transcription regulate each others’ function to ultimately determine cell fate and identity. We employ a broad range of approaches including single-particle cryo-electron microscopy (cryo-EM), X-ray crystallography, biochemistry, and genetics to mechanistically understand how these molecular assemblies regulate each other across molecular scales.
We study the interplay of gene expression and genome organization. Our work focuses on understanding how large molecular machineries involved in genome organization and gene transcription regulate each others’ function to ultimately determine cell fate and identity. We employ a broad range of approaches including single-particle cryo-electron microscopy (cryo-EM), X-ray crystallography, biochemistry, and genetics to mechanistically understand how these molecular assemblies regulate each other across molecular scales.
Research Interests
Papers共 45 篇Author StatisticsCo-AuthorSimilar Experts
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Yi Liu,Anthony Flamier,George W. Bell, Annette Jun Diao,Troy W. Whitfield, Hao-Che Wang, Yizhe Wu,Fabian Schulte,Max Friesen, Ruisi Guo,Maisam Mitalipova,X. Shawn Liu,
Neuronno. 12 (2024): 1943-1958.e10
MOLECULAR CELLno. 7 (2024): 1243-1256.e5
Markus Vogt,Nevenka Dudvarski Stankovic, Yiliam Cruz Garcia,Julia Hofstetter,Katharina Schneider, Filiz Kuybu, Theresa Hauck,Bikash Adhikari, Anton Hamann, Yamila Rocca, Lara Grysczyk, Benedikt Martin,
Gutpp.gutjnl-2023, (2024)
Markus Vogt,Nevenka Dudvarski Stankovic, Yiliam Cruz Garcia,Julia Hofstetter,Katharina Schneider, Filiz Kuybu, Theresa Hauck,Bikash Adhikari, Anton Hamann, Yamila Rocca, Lara Grysczyk, Benedikt Martin,
Gut (2024)
Journal of Biological Chemistryno. 3 (2024)
Jiawei Zhao,Liam D. Cato,Uma P. Arora,Erik L. Bao, Samuel C. Bryant,Nicholas Williams, Yuemen Jia,Seth R. Goldman,Jyoti Nangalia,Michael A. Erb,Seychelle M. Vos, Scott A. Armstrong,
Yilai Li,Quanfu Fan, Ziping Xu, Emma Rose Lee,John Cohn, Veronique Demers, Ja Young Lee,Lucy Yip,Michael A. Cianfrocco,Seychelle M. Vos
biorxiv(2023)
bioRxiv (Cold Spring Harbor Laboratory) (2023)
bioRxiv : the preprint server for biology (2023)
Nature Communicationsno. 1 (2023): 1-11
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