Sebastian Brandner - Division of Neuropathology, Queen Square Institute of Neurology, University College London

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Career Trajectory

Bio

Professor Brandner is Training Programme Director in Diagnostic Neuropathology for London, Chair of the Specialty Advisory Committee and Chair of the Working Group of Cancer Services Royal College of Pathologists. He authored a chapter in the 2021 WHO classification of CNS tumours and national guidelines for the Royal College of Pathologists.
Professor Brandner is clinically active and his department serves a population of 11 million. His molecular pathology services are comprehensive and innovative and are at the forefront in the United Kingdom.

Research Interests

Papers共 536 篇Author StatisticsCo-AuthorSimilar Experts

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Molecular Signatures Define BAP1-altered Meningioma As a Distinct CNS Tumor with Deregulation of Polycomb Repressive Complex Target Genes

Philipp Sievers,Sonali Arora,Thomas Hielscher, Dilan Savran,Daniel Schrimpf,Rouzbeh Banan, David Vonhören,Stefan Pusch,Martin Sill, Romain Appay, Hans-Georg Wirsching,Tibor Hortobagyi, Hildegard Dohmen,Till Acker,Patricia Kohlhof-Meinecke,Leonille Schweizer,Annika K Wefers,Patrick N Harter,Christian Hartmann,Rudi Beschorner,Jens Schittenhelm,Felix Behling,Ghazaleh Tabatabai,Christian Mawrin,Matija Snuderl,Sybren L N Maas,Pieter Wesseling,Sebastian Brandner,Andrey Korshunov,Miriam Ratliff,Sandro M Krieg,Wolfgang Wick,David T W Jones, Stefan M Pfister, Eric C Holland,Andreas von Deimling,Frank Szulzewsky,Felix Sahm

Neuro-oncology（2025）

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Intracellular Trafficking SNARE Protein, Syntaxin-6, is a Modifier of Prion and Tau Pathogenesis in Vivo and in Cellular Models

Elizabeth Hill, Mitali Patel, Juan M Ribes,Jacqueline Linehan,Fuquan Zhang,Michael Farmer,Tatiana Jakubcova,Shyma Hamdan,Andrew Tomlinson,Tiziana Ercolani,Christian Schmidt,Parvin Ahmed, George Thirlway,Silvia Purro, Fabio Argentina,Aline T Marinho, Emma L Jones, Nicholas Kaye, Craig Fitzhugh,Rohan de Silva,Graham S Jackson,Sebastian Brandner, Peter Kloehn,John Collinge,Thomas J Cunningham,Simon Mead

biorxiv（2025）

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Testing Meningiomas with Methylation Arrays: Insights and Recommendations from a Large Single-Centre Study

Fernanda Ruiz, Rossella Rispoli,Zane Jaunmuktane,Ashirwad Merve, Linda D'Antona, Monika Dutt,Felix Sahm,Sebastian Brandner

Neuropathology and applied neurobiologyno. 3 (2025): e70018-e70018

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VGLL Fusions Define a New Class of Intraparenchymal Central Nervous System Schwannoma

NEURO-ONCOLOGY (2025)

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ROBIN: A Unified Nanopore-Based Assay Integrating Intraoperative Methylome Classification and Next-Day Comprehensive Profiling for Ultra-Rapid Tumor Diagnosis

Simon Deacon,Inswasti Cahyani, Nadine Holmes, Graeme Fox,Rory Munro,Satrio Wibowo, Thomas Murray, Hannah Mason, Mark Housley, Daniel Martin, Abdi Sharif,Areeba Patel, Robert Goldspring,Sebastian Brandner,Felix Sahm, Stuart Smith,Simon Paine, Matthew Loose

Neuro-oncology（2025）

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Automated Diffusion Analysis for Non-Invasive Prediction of IDH Genotype in WHO Grade 2-3 Gliomas

Jiaming Wu, Stefanie C Thust, Stephen J Wastling, Gehad Abdalla, Massimo Benenati, John A Maynard,Sebastian Brandner,Ferran Prados Carrasco,Frederik Barkhof

AJNR American journal of neuroradiology (2025)

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Prospective, Multicenter Validation of a Platform for Rapid Molecular Profiling of Central Nervous System Tumors

Areeba Patel, Kirsten Göbel, Sebastian Ille, Felix Hinz, Natalie Schoebe, Henri Bogumil,Jochen Meyer, Michelle Brehm, Helin Kardo,Daniel Schrimpf,Artem Lomakin, Michael Ritter, Pauline Göller, Paul Kerbs, Lisa Pfeifer, Stefan Hamelmann,Christina Blume, Franziska M Ippen, Natalie Berghaus,Philipp Euskirchen,Leonille Schweizer,Claus Hultschig,Nadine Van Roy,Jo Van Dorpe,Joni Van der Meulen,Siebe Loontiens, Franceska Dedeurwaerdere,Henning Leske,Skarphéðinn Halldórsson, Graeme Fox, Simon Deacon,Inswasti Cahyani, Nadine Holmes,Satrio Wibowo,Rory Munro, Dan Martin, Abid Sharif, Mark Housley, Robert Goldspring,Sebastian Brandner,Somak Roy,Jürgen Hench,Stephan Frank,Andreas Unterberg,Violaine Goidts,Natalie Jäger,Simon Paine,Stuart Smith,Christel Herold-Mende,Wolfgang Wick,Stefan M Pfister,Einar O Vik-Mo,Andreas von Deimling, Sandro Krieg,David Tw Jones,Matthew Loose,Matthias Schlesner,Martin Sill,Felix Sahm

Nature medicine（2025）

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Advancing CNS Tumor Diagnostics with Expanded DNA Methylation-Based Classification

Martin Sill,Daniel Schrimpf,Areeba Patel,Dominik Sturm, Natalie Jäger, Philipp Sievers,Leonille Schweizer, Rouzbeh Banan,David Reuss, Abigail Suwala,Andrey Korshunov,Damian Stichel,Annika K Wefers,Ann-Christin Hau, Henning Boldt,Patrick N Harter,Zied Abdullaev, Jamal Benhamida,Daniel Teichmann,Arend Koch, Jürgen Hench,Stephan Frank,Martin Hasselblatt,Sheila Mansouri, Theresita Díaz de Ståhl,Jonathan Serrano, Jonas Ecker,Florian Selt,Michael Taylor,Vijay Ramaswamy, Florence Cavalli, Anna S Berghoff,Brigitte Bison, Mirjam Blattner-Johnson, Ivo Buchhalter,Rolf Buslei,Gabriele Calaminus,Nicola Dikow, Hildegard Dohmen,Philipp Euskirchen,Gudrun Fleischhack,Amar Gajjar,Nicolas U Gerber,Marco Gessi,Gerrit H Gielen,Astrid Gnekow, Nicholas G Gottardo,Christine Haberler, Stefan Hamelmann, Volkmar Hans, Jordan R Hansford,Christian Hartmann, Frank L Heppner, Pablo Hernaiz Driever,Katja von Hoff, Ulrich W Thomale,Stephan Tippelt,Michael C Frühwald,Christof M Kramm,Ulrich Schüller,Jens Schittenhelm,Martin U Schuhmann,Marco Stein, Petra Ketteler,Marc Ladanyi,Nada Jabado,Barbara C Jones,Chris Jones,Matthias A Karajannis,Ralf Ketter,Patricia Kohlhof,Uwe Kordes,Annekathrin Reinhardt, Christian Kölsche,Katrin Lamszus,Peter Lichter,Sybren L N Maas,Christian Mawrin,Till Milde,Michel Mittelbronn,Camelia-Maria Monoranu,Wolf Mueller,Martin Mynarek,Paul A Northcott,Kristian W Pajtler,Werner Paulus,Arie Perry, Ingmar Blümcke,Karl H Plate,Michael Platten,Matthias Preusser,Torsten Pietsch,Marco Prinz,Guido Reifenberger, Bjarne W Kristensen,Marcel Kool,Volker Hovestadt,David W Ellison,Thomas S Jacques,Pascale Varlet,Nima Etminan,Till Acker,Michael Weller,Christine L White,Olaf Witt,Christel Herold-Mende, Jürgen Debus, Sandro Krieg,Wolfgang Wick,Matija Snuderl,Ken Aldape,Sebastian Brandner,Cynthia Hawkins, Craig Horbinski, Christian Thomas,Pieter Wesseling,Andreas von Deimling,David Capper, Stefan M Pfister,David Tw Jones,Felix Sahm

medRxiv the preprint server for health sciences (2025)

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IDH-mutant Astrocytomas with Primitive Neuronal Component Have a Distinct Methylation Profile and a Higher Risk of Leptomeningeal Spread

Acta Neuropathologicano. 1 (2025): 1-13

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PRNP E146G Mutation Inherited Prion Disease: Distinctive Clinical, Pathological and Fluid Biomarker Features

Thomas Coysh,Zane Jaunmuktane, Laszlo L. P. Hosszu, Nour Majbour, Fuquan Zhang, Tracy Campbell, Lee Darwent, Marcelo Barria Matus, Edgar Chan, Leah Holm-Mercer,Tze How Mok,Jonathan D. F. Wadsworth,Jan Bieschke, Kannan Nithi,Sebastian Brandner,Colin Smith,Margaret Esiri,John Collinge,Simon Mead

Journal of Neurologyno. 4 (2025): 1-10

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