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Bio
The underlying theme of Sean's managerial and research interests has been to find methods to make best use of synchrotron lightsources in general, and in particular to reveal the complexity of biological systems, and make these methods accessible to the broadest possible community. The latest manefestation of these interests can be seen in the program for life sciences at NSLS-II and with cryogenic electron microscopy, he recently initiated a new program for imaging biological systems using quantum properties of light
Sean has constructed and operated x-ray beamlines for macromolecular crystallography at synchrotron sites since 1991. Initially developing methods for the routine use of anomalous dispersion in the elucidation of macromolecular structure. He has made significant contributions to the automation of synchrotron beamlines and the understanding of the fundamental processes occurring when intense x-ray beams meet macromolecular crystals. He continues efforts in this area with the goal of providing increasingly automated and reliable macromolecular structure determination facilities whilst dealing with the issues of “real” samples.
Research Interests
Papers共 191 篇Author StatisticsCo-AuthorSimilar Experts
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PHOTONICSno. 3 (2024): 252
JOURNAL OF SYNCHROTRON RADIATIONno. Pt 6 (2022): 1480-1494
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