基本信息
views: 709
Career Trajectory
Bio
We are interested in deciphering the evolutionary history of life by comparative analysis of genome sequences. Our research currently focuses on the development of computational methods for RNA, protein, and genome sequence analysis. We use probabilistic modeling approaches to build statistical models of interesting biological features, and use such models for Bayesian or likelihood-based statistical inference in large scale genome analysis and annotation.
We are currently working in three general areas. One area is RNA structure and function. We are developing new methods for RNA homology detection, RNA structure prediction, and identification of conserved RNA structures by comparative genome sequence analysis (including both noncoding RNA genes and cis-regulatory RNA structures). A second area is the improvement of methods for remote protein homology detection, implemented in our HMMER software package. Finally, more recently we have begun collaborating with neuroscientists on the analysis of neural cell-type-specific genomic data, aiming to learn more about the evolution and development specification of neuronal cell types.
We are currently working in three general areas. One area is RNA structure and function. We are developing new methods for RNA homology detection, RNA structure prediction, and identification of conserved RNA structures by comparative genome sequence analysis (including both noncoding RNA genes and cis-regulatory RNA structures). A second area is the improvement of methods for remote protein homology detection, implemented in our HMMER software package. Finally, more recently we have begun collaborating with neuroscientists on the analysis of neural cell-type-specific genomic data, aiming to learn more about the evolution and development specification of neuronal cell types.
Research Interests
Papers共 328 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Camille Cohen,Rana Mhaidly, Hugo Croizer,Yann Kieffer,Renaud Leclere,Anne Vincent-Salomon, Catherine Robley, Dany Anglicheau, Marion Rabant,Aurélie Sannier,Marc-Olivier Timsit,Sean Eddy,
Nature Communicationsno. 1 (2024): 1-23
Anna Reznichenko,Viji Nair,Sean Eddy,Damian Fermin,Mark Tomilo, Timothy Slidel,Wenjun Ju, Ian Henry,Shawn S. Badal, Johnna D. Wesley,John T. Liles,Sven Moosmang,
Jonathan P. Troost, Jennifer D’Souza,Miatta Buxton,Abhijit V. Kshirsagar,Lawrence S. Engel, Cassandra R. O’Lenick,William E. Smoyer,Jon Klein,Wenjun Ju,Sean Eddy,Margaret Helmuth,Laura H. Mariani,
Kidney International Reports (2024)
Joonho Yoon,Zhenan Liu, Mathew Alaba,Leslie A Bruggeman,Paul Janmey, Carlos Arana, Oluwatoyosi Ayenuyo, Isabela Medeiros,Viji Nair,Sean Eddy,Matthias Kretzler,Joel M Henderson,
bioRxiv : the preprint server for biology (2024)
KIDNEY INTERNATIONALno. 2 (2024): 218-230
NATUREno. 8007 (2024): 271-273
Benjamin A. Juliar,Ian B. Stanaway, Fumika Sano,Hongxia Fu,Kelly D. Smith,Shreeram Akilesh, Suzie J. Scales,Jamal El Saghir,Pavan K. Bhatraju,Esther Liu, Johnson Yang,Jennie Lin,
Cell Reportsno. 6 (2024): 114310-114310
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn