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Bio
Dr. Magness’ research is focused on the basic biology of intestinal stem cells, the genes that control their behavior, and translational approaches to stem cell based therapies for human disease and injury of the intestine. Furthermore his research focuses on elucidating genetic mechanisms underlying stemness and developing translational models to establish a finer understanding of stem cell-driven regeneration dynamics in homeostasis and injury. Using a combination of genetic mouse models and micro-frabricated bioengineered platforms, Dr. Magness’ team is exploiting the self-renewal capacity and multi-potency of ISCs to develop long-term ex vivo models of the intestine and colon with primary tissues. These biomimetic models offer new solutions for compound screening and cell-based therapies
Research Interests
Stem Cell Biology
Niche Dynamics
Tissue Engineering
Biomimetic Scaffolds
Single-Cell Biology
Stem cell maintenance and differentiation
Single cell analytics
High-throughput biomimetic culture platforms
Research Interests
Papers共 148 篇Author StatisticsCo-AuthorSimilar Experts
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Gastroenterologyno. 5 (2024): S-382
Physiologyno. S1 (2024)
Kristina R. Rivera,R. Jarrett Bliton,Joseph Burclaff,Michael J. Czerwinski,Jintong Liu, Jessica M. Trueblood,Caroline M. Hinesley,Keith A. Breau,Halston E. Deal, Shlok Joshi,Vladimir A. Pozdin, Ming Yao,
Cellular and Molecular Gastroenterology and Hepatologyno. 5 (2023): 823-846
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Communications biologyno. 1 (2023): 878-878
Deniz Coskuner, James B. Collins, Quinn Fong, Meredith J. Zeller, Andrew Lucas, Benyam Muluneh,Scott T. Magness, Aadra P. Bhatt
Gastroenterologyno. 6 (2023): S-472
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGYno. 4 (2023): G262-G280
Kristina R Rivera,R Jarrett Bliton,Joseph Burclaff,Michael J Czerwinski,Jintong Liu, Jessica M Trueblood,Caroline M Hinesley,Keith A Breau,Halston E Deal, Shlok Joshi,Vladimir A Pozdin,Ming Yao,
Cellular and molecular gastroenterology and hepatologyno. 5 (2023): 823-846
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGYno. 4 (2023): G262-G280
Gastroenterologyno. 6 (2023): S-130
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