基本信息
浏览量:2
职业迁徙
个人简介
Research
Plants have a variety of mechanisms they use to defend themselves against pathogens and pests. These defenses can sometimes be manipulated genetically to develop resistant crop varieties, an economical and environmentally friendly way to control disease. Pathogenic organisms are constantly evolving, however, and typically become virulent on these resistant varieties. An understanding of how resistance and virulence evolves in natural and managed populations helps us determine which types of resistances will remain effective for a useful period.
Bacteria and fungi secrete proteins to help them utilize their substrates and some plant pathogens secrete these directly into plant cells. The roles of most of these effector proteins are to overcome plant defenses. These are also detected by plant resistance gene products that have roles in pathogen recognition. One of our research programs is using a genomics approach to identify and characterize effector proteins from the stripe rust fungus, an important pathogen that affects wheat worldwide. Characterization of these effector proteins is a key to understanding the basic mechanisms of pathogenicity in these biotrophic fungi. We hope this will indicate why some cereals, like rice, are not attacked by rust fungi while most other cereals are. Ultimately, we would like to utilize the defense mechanisms of rice in cereals like wheat.
Some cultivated species (e.g. wheat) have little variation in their resistance to certain important pathogens, so sources of genetic resistance are not available. We therefore try to find resistance in related species and try to transfer this resistance to the cultivated types. Another approach we are trying, for soil borne pathogens, is to identify genotypes or cultural conditions that favor microbes that are able to suppress the pathogenic microbes. We are using high throughput DNA pyrosequencing approaches to characterize microbial populations in soil and to identify the microbes that are most important.
Plants have a variety of mechanisms they use to defend themselves against pathogens and pests. These defenses can sometimes be manipulated genetically to develop resistant crop varieties, an economical and environmentally friendly way to control disease. Pathogenic organisms are constantly evolving, however, and typically become virulent on these resistant varieties. An understanding of how resistance and virulence evolves in natural and managed populations helps us determine which types of resistances will remain effective for a useful period.
Bacteria and fungi secrete proteins to help them utilize their substrates and some plant pathogens secrete these directly into plant cells. The roles of most of these effector proteins are to overcome plant defenses. These are also detected by plant resistance gene products that have roles in pathogen recognition. One of our research programs is using a genomics approach to identify and characterize effector proteins from the stripe rust fungus, an important pathogen that affects wheat worldwide. Characterization of these effector proteins is a key to understanding the basic mechanisms of pathogenicity in these biotrophic fungi. We hope this will indicate why some cereals, like rice, are not attacked by rust fungi while most other cereals are. Ultimately, we would like to utilize the defense mechanisms of rice in cereals like wheat.
Some cultivated species (e.g. wheat) have little variation in their resistance to certain important pathogens, so sources of genetic resistance are not available. We therefore try to find resistance in related species and try to transfer this resistance to the cultivated types. Another approach we are trying, for soil borne pathogens, is to identify genotypes or cultural conditions that favor microbes that are able to suppress the pathogenic microbes. We are using high throughput DNA pyrosequencing approaches to characterize microbial populations in soil and to identify the microbes that are most important.
研究兴趣
论文共 85 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
BMC research notesno. 1 (2023): 1-3
Phytobiomes Journalno. 1 (2022): 100-112
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn