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个人简介
Dr. Kumbar PhD is a Professor with academic tenure in the Departments of Orthopedic Surgery, Materials Science & Engineering and Biomedical Engineering at the University of Connecticut. His research is focused on the synthesis and characterization of novel biomaterials for tissue engineering and drug delivery applications. The Kumbar laboratory specializes in the fabrication and characterization of micro nanostructures, with a focus on semi-synthetic polymers for tissue engineering and drug delivery applications. Semi-synthetic polymers consisting of synthetic and natural-based materials integrate the advantageous mechanical properties of synthetic materials while preserving the inherent biological functions of natural materials. These novel materials are fabricated into micro nanostructures to promote enhanced tissue regeneration and controlled drug delivery systems. His published work has been well cited over 9000 citations with an h index of 54.
Dr. Kumbar is an active member of the Society for Biomaterials (SFB), Controlled Release Society (CRS), Materials Research Society (MRS), and Orthopaedic Research Society (ORS). Dr. Kumbar has co-edited there textbooks namely “Natural and Synthetic Biomedical Polymers” Elsevier Science & Technology, 2014- ISBN: 978-0-12-396983-5, Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine ISBN: 9780128033944 and Artificial Protein and Peptide Nanofibers ISBN: 9780081028506. He is an Associate Editor of Bioactive Materials and Journal of Biomedical Nanotechnology, He also on the Editorial Board of Journal of Biomedical Materials Research-Part B, Journal of Applied Polymer Science and Journal of Biomedical Engineering Express that represent biomaterials research. Dr. Kumbar has dedicated his significant efforts in teaching and mentoring high school, undergraduate, and graduate students as well as postdoctoral fellows.
Current ongoing projects in the laboratory include:
Tendon Regeneration
By recapitulating the natural environment of tissues through use of materials, cells and biochemical cues, it is possible to regenerate tendon tissue. Our electrospun fiber matrices are developed to provide a biomimetic environment to house and deliver cells and biologic factors to improve healing and regeneration.
Nerve Regeneration
The lab focuses on the development of conducting, degradable polymers for the regeneration of nerve tissue. The slow regenerative nature of nerve tissue poses particular challenges to the clinical world as nerve injuries onset by pain, trauma, and/or degeneration rarely heal to suitable functional conditions. The lab develops, characterizes, and tests conducting polymeric scaffolds in conjunction with electrical stimulation techniques and stem-cell strategies to enhance the rate and efficacy of nerve tissue regeneration.
Bone Regeneration
The lab aims to utilize cellulose, the most abundant biopolymer, to serve as a mechanically competent platform for bone regeneration. The lab has been successful in creating a mechanically competent cellulosic scaffold platform to serve as a material for bone regeneration. The combination of natural polymers with micro and nanoscale features enhanced the regenerative abilities of the scaffolds both in vitro and in vivo. Current investigations aim to improve the properties of these natural polymeric materials.
研究兴趣
论文共 163 篇作者统计合作学者相似作者
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GELSno. 1 (2024): 62
BIOACTIVE MATERIALS (2024): 181-207
Aleksandra A. Golebiowska,Jonathon T. Intravaia, Vinayak M. Sathe,Sangamesh G. Kumbar,Syam P. Nukavarapu
BIOACTIVE MATERIALS (2024): 98-123
AAPS Introductions in the Pharmaceutical Sciencespp.159-182, (2023)
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Aimee L. Dowling,Stuart Walbridge, Celine Ertekin,Sriya Namagiri, Krystal Camacho,Ashis Chowdhury,Jean-Paul Bryant, Eric Kohut,John D. Heiss,Desmond A. Brown,Sangamesh G. Kumbar,Yeshavanth Kumar Banasavadi-Siddegowda
Cellsno. 21 (2023): 2562-2562
Journal of functional biomaterialsno. 2 (2023): 52-52
Sama Abdulmalik,Jack Gallo,Jonathan Nip,Sara Katebifar, Michael Arul,Amir Lebaschi, Lucas N Munch,Jenna M Bartly, Shilpa Choudhary,Ivo Kalajzic,Yeshavanth Kumar Banasavadi-Siddegowdae,Syam P Nukavarapu,
Michael R Arul,Ibtihal Alahmadi,Daylin Gamiotea Turro,Aditya Ruikar, Sama Abdulmalik,Justin T Williams,Basavaraju G Sanganahalli,Bruce T Liang, Rajkumar Verma,Sangamesh G Kumbar
Biomaterials scienceno. 24 (2023): 7856-7866
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