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个人简介
* I received my PhD from CNIO-UCM in Madrid in 2004 and subsequently worked as a Post- Doctoral Fullbright Fellow at the MRC-LMB, Cambridge (UK), from 2005-2007. I have been a Senior Researcher at CNIO since 2008 and became the Head of the Molecular Cytogenetics & Genome Engineering Unit at the Spanish National Cancer Centre (CNIO) in 2017.
* My research interests in cytogenetics and gene editing have contributed significantly to the field, including:
1.- generation of cellular and animal models that recapitulate and study cancer-related chromosomal aberrations (Torres R et al. Nat Commun 2014; Stem Cell Rep 2017. Senior author both)
2.- identification of novel therapeutic targets and develop novel CRISPR-based cancer therapy options (Nat Commun. 2020. Senior author)
3.- increment of our knowledge of the underlying mechanisms of cancer (epi)cyto-genetic alterations (over 80 articles published in top international journals: Nat Commun, Gut, J Clin Invest, Cell Metab, EMBO Mol Med, Nat Cancer, NAR or Blood).
Scientific publications: 87 Senior author publications: 9 (research) + 4 (reviews) Total citations: 3.707 H index: 34 i10 index: 56
Editor or author of 5 chapters of genetic medicine and editor of a CRISPR system book
* I have been IP of 3 FIS-ISCIII-FEDER, 1 RTICC, 1 Caixa-Impulse, 1 Explora, 1 DTS- ISCIII, and 1 AECC_Lab projects, in addition to obtaining funding from 5 private entities (over
1.000.000€). I have delivered numerous conferences at national and international meetings.
* I am working on projects with an innovative edge, trying to develop and valorized
translational products. 3 patent fillings (EP18382746.8; EP21382876.7; and P200401894)
* In 2021, my group was awarded the Molecular Cloud Infinite Possibilities Teams Award for Genome Editing, and one of our publications received the 1st prize in the "Paper of the Year 2020-2021" contest in gene therapy by the SETGyC. I have been the recipient of a Caixa Impulse prize for our development of new therapy options targeting cancer chromosomal translocations in 2018. I am currently enrolled in an “Instituto Empresa” Master: IE Accelerate: From Tech to Business. I am a member of the Director Board of the SETGyC. I obtained Human Genetics Accreditation (AEGH, 2010), and “Mencion de Biólogo Sanitario” (COBCM, 2022).
I have combined my research with cancer genetic diagnosis duties in collaboration with 5 National Health System Hospitals.
* I am a teacher in 5 Master programs in Biotechnology and Genetics of Cancer (UCM, UAM, UAH, European School of Oncology, and CEU). I have supervised 12 TFM and 1 PhD thesis, and currently directing 3 PhD thesis. I have also supervised 11 technicians, and more than 30 MIR/BIR students during the last 5 years.
研究兴趣
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iScienceno. 4 (2024): 109530-109530
Nature communicationsno. 1 (2024): 3931-3931
Pedro Roda-Navarro,Álvaro Gómez-Morón,Sergio Alegre-Gómez,Rocio Ramirez-Muñoz, Alicia Hernaiz-Esteban,Carlos Carrasco-Padilla, Camila Scagnetti,Óscar Aguilar-Sopeña, Marta García-Gil,Aldo Borroto,Raul Torres-Ruiz,Sandra Rodríguez-Perales,
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British journal of haematology (2023)
MOLECULAR THERAPYno. 4 (2023): 724-724
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Lucia Morgado-Palacin,Jessie A Brown,Thomas F Martinez,Juana M Garcia-Pedrero,Farhad Forouhar,S Aidan Quinn,Clara Reglero,Joan Vaughan, Yasamin Hajy Heydary,Cynthia Donaldson,Sandra Rodriguez-Perales,Eva Allonca,
Bloodno. 20 (2023): 1752-1756
Frontiers in immunology (2023): 1185517
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