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My research revolves around microbe-induced host cell reprogramming by effector proteins that are shuttled into plant cells. Effectors are a hallmark for animal and plant pathogens’ success in conquering the host. Plant populations frequently maintain counter-defensive disease resistance proteins (R proteins) for intracellular recognition of effectors. Studying R protein mechanisms thus reveals plant strategies in coping with constant pathogen challenge.
During my masters and Ph.D. studies with Thomas Lahaye in Halle I characterised the tomato TIR-NB-LRR protein Bs4. Bs4 confers resistance towards the bacterial pathogen Xanthomonas campestris pv vesicatoria. Xanthomonads are the causal agents of economically important bacterial plant diseases in tomato, pepper, citrus and rice. Tomato Bs4-mediated resistance is achieved by cytoplasmic recognition of a set of Xanthomonas-translocated transcription activator-like (TAL) effector proteins.
During my masters and Ph.D. studies with Thomas Lahaye in Halle I characterised the tomato TIR-NB-LRR protein Bs4. Bs4 confers resistance towards the bacterial pathogen Xanthomonas campestris pv vesicatoria. Xanthomonads are the causal agents of economically important bacterial plant diseases in tomato, pepper, citrus and rice. Tomato Bs4-mediated resistance is achieved by cytoplasmic recognition of a set of Xanthomonas-translocated transcription activator-like (TAL) effector proteins.
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Papers共 113 篇Author StatisticsCo-AuthorSimilar Experts
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biorxiv(2024)
Yen-Ting Lu,Jeanne Loue-Manifel,Norbert Bollier,Philippe Gadient,Freya De Winter,Philip Carella,Antoine Hoguin, Shona Grey-Switzman,Hugo Marnas, Francois Simon, Alice Copin, Shelby Fischer,
Current biology : CBno. 4 (2024): 793-807.e7
Journal of experimental botany (2024)
The Plant cellno. 7 (2024): 2491-2511
Mara Sgroi,David Hoey, Karina Medina Jimenez,Sarah L Bowden, Matthew Hope,Emma J Wallington,Sebastian Schornack,Armando Bravo,Uta Paszkowski
Proceedings of the National Academy of Sciences of the United States of Americano. 30 (2024): e2318982121-e2318982121
Proceedings of the National Academy of Sciencesno. 41 (2023)
Current opinion in plant biology (2023): 102469-102469
Cell Host & Microbeno. 5 (2023): 683-684
Trends in plant scienceno. 6 (2023): 650-661
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