基本信息
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Career Trajectory
Bio
Research Areas: Antibiotic resistance, Microbiology, Staphylococcus spp., Salmonella
Salmonella, Staphylococcus schleiferi, Streptococcus, E. coli, antibiotic resistance, methicillin resistance, MRSA, MRSP, molecular diagnostics, pulsed-field gel electrophoresis (PFGE), LAMP, PCR, molecular epidemiology, One Health, skin microbiome, atopic dermatitis, molecular serotyping, genome sequencing, zoonoses, extended spectrum beta-lactamase genes (ESBL)
RESEARCH INTERESTS
My lab uses a One Health approach to study the molecular epidemiology of common bacterial pathogens of companion animals and horses. We focus primarily on discriminatory molecular typing methods to study the epidemiology of Staphylococcus species, Salmonella and E.coli We work with Staphylococcus schleiferi and S. aureus and have contributed to the veterinary dermatology community by characterizing strains that are commonly found in pets and humans. We recently published 4 whole genome sequences of S. schleiferi. We study methicillin resistant staphylococci in animals and the potential of these drug resistant pathogens to be transmitted to humans and vice versa. Skin microbiome studies with dogs that suffer from atopic dermatitis have shown that dogs are a good model for AD in children. Similar molecular methods are used to characterize Salmonella strains isolated from animals and molecular serotyping is use in the lab. We also study the mechanisms of transferable and non-transferable antimicrobial resistance genes of Salmonella and E.coli and have published some of the first reports of ESBL genes in isolates from animals. My research also includes the development, validation and verification of molecular diagnostic assays, for the diagnosis of infectious disease in animals. I am particularly interested in development of point-of-care assay and we have recently evaluated loop mediated isothermal PCR (LAMP) for the detection of Streptococcus equip in the guttural pouch of horses.
Salmonella, Staphylococcus schleiferi, Streptococcus, E. coli, antibiotic resistance, methicillin resistance, MRSA, MRSP, molecular diagnostics, pulsed-field gel electrophoresis (PFGE), LAMP, PCR, molecular epidemiology, One Health, skin microbiome, atopic dermatitis, molecular serotyping, genome sequencing, zoonoses, extended spectrum beta-lactamase genes (ESBL)
RESEARCH INTERESTS
My lab uses a One Health approach to study the molecular epidemiology of common bacterial pathogens of companion animals and horses. We focus primarily on discriminatory molecular typing methods to study the epidemiology of Staphylococcus species, Salmonella and E.coli We work with Staphylococcus schleiferi and S. aureus and have contributed to the veterinary dermatology community by characterizing strains that are commonly found in pets and humans. We recently published 4 whole genome sequences of S. schleiferi. We study methicillin resistant staphylococci in animals and the potential of these drug resistant pathogens to be transmitted to humans and vice versa. Skin microbiome studies with dogs that suffer from atopic dermatitis have shown that dogs are a good model for AD in children. Similar molecular methods are used to characterize Salmonella strains isolated from animals and molecular serotyping is use in the lab. We also study the mechanisms of transferable and non-transferable antimicrobial resistance genes of Salmonella and E.coli and have published some of the first reports of ESBL genes in isolates from animals. My research also includes the development, validation and verification of molecular diagnostic assays, for the diagnosis of infectious disease in animals. I am particularly interested in development of point-of-care assay and we have recently evaluated loop mediated isothermal PCR (LAMP) for the detection of Streptococcus equip in the guttural pouch of horses.
Research Interests
Papers共 160 篇Author StatisticsCo-AuthorSimilar Experts
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JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATIONno. 1 (2024): 124-127
Greene's Infectious Diseases of the Dog and Catpp.2-2, (2023)
Journal of equine veterinary science (2023): 104893-104893
Elsevier eBookspp.510-512, (2023)
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Katlyn M Lake,Shelley C Rankin,Wayne S Rosenkrantz, Lakshmi Sastry,Megan Jacob, Dubra Diaz Campos,Kelli Maddock,Stephen D Cole
American journal of veterinary researchno. 9 (2023): 1-8
Veterinary dermatologyno. 1 (2022): 22-27
Elsevier eBookspp.64-71, (2021)
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