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Bio
His research covers broad areas of innate immunity, inflammation biology and host-pathogen interactions with a specific focus on macrophage immunobiology and its activation. His research unravelled novel mechanisms of macrophage activation identified regulatory pathways that limit excessive macrophage activation and showed how the imbalance between macrophage activation and regulation contributes to various inflammatory pathologies. More recently, he is using human induced pluripotent stem cells (iPSCs) as a model system to study cellular and molecular mechanisms of various immune-mediated diseases.
His group has developed methods for differentiating human induced pluripotent stem cells into various innate immune cell types (macrophages, dendritic cells and neutrophils) and organotypic cultures such as 3D intestinal organoids. Using genetically engineered iPSCs or iPSCs generated from a rare patient with immunodeficiency or inflammatory disorders his group is trying to understand the mechanism of how specific human genetic mutations influence innate immune response and disease pathogenesis.
Subho was trained by a number of world-leading scientists at Oxford, Cambridge and Harvard; he has published his research in top ranking international journals and received a number of prestigious studentships, fellowships and international awards from scientific societies. He has a strong commitment towards training and mentoring of the next generation of scientists and always welcome informal enquiries from prospective students and postdoctoral trainees.
His group has developed methods for differentiating human induced pluripotent stem cells into various innate immune cell types (macrophages, dendritic cells and neutrophils) and organotypic cultures such as 3D intestinal organoids. Using genetically engineered iPSCs or iPSCs generated from a rare patient with immunodeficiency or inflammatory disorders his group is trying to understand the mechanism of how specific human genetic mutations influence innate immune response and disease pathogenesis.
Subho was trained by a number of world-leading scientists at Oxford, Cambridge and Harvard; he has published his research in top ranking international journals and received a number of prestigious studentships, fellowships and international awards from scientific societies. He has a strong commitment towards training and mentoring of the next generation of scientists and always welcome informal enquiries from prospective students and postdoctoral trainees.
Research Interests
Papers共 82 篇Author StatisticsCo-AuthorSimilar Experts
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Bethany R. Bareham, Matthew Dibble, Leila Mouhib, Aitor Bermejo Arteagabeitia,Subhankar Mukhopadhyay,Maddy Parsons
Cancer Researchno. 6_Supplement (2024): 5569-5569
Biomaterials scienceno. 1 (2024): 151-163
biorxiv(2024)
European Journal of Immunologyno. 6 (2024): e2350771-e2350771
NATURE (2023)
Cited7Views0Bibtex
7
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biorxiv(2023)
Natureno. 7979 (2023): E42-E42
Siamon Gordon, Matthew W.H. Chung,Scarlett L. Harris,Fernando Martinez-Estrada,Subhankar Mukhopadhyay
Reference Module in Life Sciencespp.644-661, (2022)
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Author Statistics
#Papers: 84
#Citation: 4031
H-Index: 32
G-Index: 59
Sociability: 6
Diversity: 3
Activity: 48
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