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个人简介
Research Interests
Several metalloenzymes are implicated in various diseases, including arthritis, heart disease, cancer, and others. Compounds containing ligands that bind to the catalytic metal ion in these metalloenzymes can act as effective inhibitors of potential therapeutic value. Our investigations focus on the design, synthesis, and evaluation of novel metalloprotein inhibitors based on new ligands for binding the active site metal ions.
We study the design, preparation, and properties of metal-organic frameworks (MOFs). MOFs are a class of advanced materials that may be useful in a variety of technological applications. We use organic chemistry to modify the surface and interior of MOFs in order to tune and optimize their physical and chemical properties.
Several metalloenzymes are implicated in various diseases, including arthritis, heart disease, cancer, and others. Compounds containing ligands that bind to the catalytic metal ion in these metalloenzymes can act as effective inhibitors of potential therapeutic value. Our investigations focus on the design, synthesis, and evaluation of novel metalloprotein inhibitors based on new ligands for binding the active site metal ions.
We study the design, preparation, and properties of metal-organic frameworks (MOFs). MOFs are a class of advanced materials that may be useful in a variety of technological applications. We use organic chemistry to modify the surface and interior of MOFs in order to tune and optimize their physical and chemical properties.
研究兴趣
论文共 483 篇作者统计合作学者相似作者
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Hyunyong Kim,Seth M Cohen
Inorganic chemistryno. 4 (2024): 1853-1857
Michelle R. Doyle,Selen Dirik,Angelica R. Martinez, Talyn E. Hughes, Mohini R. Iyer,Elizabeth A. Sneddon,Hyeonglim Seo,Seth M. Cohen,Giordano de Guglielmo
NEUROPHARMACOLOGY (2024): 109770-109770
Minjung Kang,Seth M Cohen
Journal of visualized experiments : JoVE (2024)
ANGEWANDTE CHEMIE-INTERNATIONAL EDITIONno. 9 (2024): e202317062-e202317062
Biochemistryno. 3 (2024): 264-272
ACS MEDICINAL CHEMISTRY LETTERSno. 1 (2023): 75-82
CHEMICAL SCIENCEno. 36 (2023): 9978-9979
Chemical scienceno. 36 (2023): 9978-9979
Journal of visualized experiments : JoVE (2023)
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作者统计
#Papers: 486
#Citation: 30821
H-Index: 89
G-Index: 169
Sociability: 7
Diversity: 3
Activity: 117
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