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个人简介
Our translational human microbiome research program focuses on gastrointestinal and airway microbiome interactions with host immunity that promote or prevent development/maintenance of chronic inflammatory disease. Taking a "populations to molecules" approach we leverage the microbiome to determine the origins of childhood allergy and asthma and the early life molecular and cellular drivers of immune dysfunction that lead to childhood disease development. We also leverage human population studies and clinical trials to gain insights into the role of the gut microbiome in inflammatory bowel disease. Our studies allow us to develop rationally designed microbial therapeutics, leading to the founding of Siolta Therapeutics which is currently testing a lead product developed in our lab for the prevention of childhood allergy and asthma.
研究兴趣
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crossref(2024)
Jennifer Claytor,Din L. Lin,Kevin M. Magnaye, Yanedth E. Sanchez Guerrero, Charles Langelier,Susan Lynch,Najwa El-Nachef
Gastroenterologyno. 5 (2024): S-177
Journal of immunology research (2024): 2506586-2506586
Sandra Hertz,Jacqueline Moltzau Anderson, Darren Dumlao,Hans L. Nielsen, claire Schachtschneider,Kathryn E. McCauley,Mustafa Özçam,Lone Larsen,Susan Lynch,Henrik Nielsen
Gastroenterologyno. 5 (2024): S-1534
Kathryn E McCauley,Juliana Durack,Kole V Lynch,Douglas W Fadrosh,Kei E Fujimura, Faith Vundla,Mustafa Özçam,Petra LeBeau, Agustin Caltroni, Preston Burns,Hoang T Tran,Leonard B Bacharier,
The Journal of allergy and clinical immunologyno. 6 (2024): 1563-1573
GUT MICROBESno. 1 (2024): 2290661-2290661
NEUROPSYCHOPHARMACOLOGY (2023): 248-249
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