S Le - Division of Medical Genetics, Department of Pediatrics, Harbor-UCLA Research and Education Institute, Torrance CA, USA

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36. Intrathecal enzyme replacement therapy treats meningeal storage and spinal cord compression in MPS I dogs

Patricia Dickson,N.M. Ellinwood, A. Dierenfeld, K. Kline, J. Parkes,S. Hanson,C. Vite,A. Mlikotic, A. Chen, W. Gross,M. Haskins,K. Ponder,

Molecular Genetics and Metabolismno. 2 (2010)

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INTRAVENOUS ENZYME REPLACEMENT THERAPY IMPROVES CARDIAC VALVULAR STORAGE IN MPS I DOGS TREATED FROM BIRTH

S. Shah,N. M. Ellinwood, A. Dierenfeld,M. McEntee,J. Jens, E. Snella,W. A. Ware, L. Moran,M. Passage,S. Le,P. I. Dickson

MOLECULAR GENETICS AND METABOLISM（2009）

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INTRATHECAL ENZYME REPLACEMENT THERAPY MAY STABILIZE OR REVERSE SIGNS OF SPINAL CORD COMPRESSION IN MPS I DOGS

P. I. Dickson,N. M. Ellinwood,S. Hanson,C. Vite,M. Passage,S. Le, C. Guerra

MOLECULAR GENETICS AND METABOLISM（2009）

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Intrathecal recombinant human a-L-iduronidase alleviates spinal cord compression symptoms and is well-tolerated in attenuated MPS I patients

P. I. Dickson,D. Naylor,A. Mlikotic, A. Victoroff,A. Chen,M. Passage,S. Le

MOLECULAR GENETICS AND METABOLISMno. 3 (2008): 247-247

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Quarterly intrathecal enzyme replacement therapy for canine MPS

IP Dickson,M McEntee,S Le, C Guerra,S Hanson, M Peinovich,M Passage,E Kakkis

MOLECULAR GENETICS AND METABOLISMno. 3 (2005): 216-216

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Immune tolerant mucopolysaccharidosis I-affected dogs have improved glycosaminoglycan storage reduction with enzyme replacement therapy

M Peinovich,M McEntee,S Le,T Lester,M Passage,E Kakkis

MOLECULAR GENETICS AND METABOLISMno. 3 (2005): 234-234

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Intrathecal enzyme replacement therapy reduces lysosomal storage in the brain and meninges of the canine model of MPS I

E Kakkis,M McEntee, C Vogler,S Le,B Levy,P Belichenko,W Mobley,P Dickson,S Hanson,M Passage

Molecular Genetics and Metabolismno. 1-2 (2004): 163-74

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160

Reduction Of Lysosomal Storage In Brain And Meninges Following Intrathecal Adminsitration Of Iduronidase In Canine Mucopolysaccharidosis I (Mpsi)

E Kakkis,M Passage,P Belichenko,M Mcentee,S Le, C Vogler, R Esquivel,W Mobley

GENETICS IN MEDICINE（2004）

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