Dr. Lam’s research focuses on early detection and chemoprevention of lung cancer. His long-term goal is to translate scientific research in lung cancer screening to implementation at the population level and to improve lung cancer outcome. He is currently the PI of the International Lung Screen Trial involving Canada, Australia, Hong Kong and Spain. He and his colleagues in the Pan-Canadian Early Detection of Lung Cancer Study Network have developed and prospectively validated a web-based lung cancer risk prediction tool to identify smokers at sufficient risk for screening with low dose CT and to evaluate the incremental value of blood and exhaled breath biomarkers. A highly accurate lung nodule malignancy risk calculator was developed to estimate the likelihood of lung cancer to guide management. He is part of a team to use radiomics and deep learning tools to address the important issue of screening interval and duration.