基本信息
views: 25
Career Trajectory
Bio
My research program has clinical and basic/translational research foci. The clinical focus is closely tied to my clinical activity in the Motherisk at the Hospital for Sick Children in collaboration with Dr. Koren. Prospective cohort studies in drug safety during lactation are conducted. Recently, we have proposed a population pharmacokinetics modeling and simulation approach to provide population estimates of infant exposures to drugs in mother's milk as a valid risk assessment tool. Mechanistic aspects of drug excretion into milk are investigated using in vitro and in vivo approaches within the framework of Transporter biology (CIHR-funded: Drugs and Human Milk). We specifically examine various nutrient transporters and the Breast Cancer Resistance Protein. The ultimate goal is to develop an approach to reduce toxin transport into milk using nutrient substrates of the drug transporters.
Research Interests
Papers共 471 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Iris Cohn, Olivia Moran,Kaitlin Stanley,Sierra Scodellaro, April Kennedy,Roozbeh Manshaei,Ruud Verstegen,Shinya Ito,Rebekah Jobling,Tamorah Lewis,Raymond Kim
Genetics in Medicine Open (2024): 101373
Cindy H. T. Yeung,Julie Autmizguine,Pooja Dalvi, Audrey Denoncourt,Shinya Ito, Pamela Katz, Mehzabin Rahman, Yves Theoret,Andrea N. Edginton
CLINICAL PHARMACOKINETICSno. 3 (2024): 317-332
Expert opinion on drug metabolism & toxicologyno. 5 (2023): 269-283
Clinical pharmacokineticsno. 11 (2023): 1611-1619
Britt I Drögemöller,Galen E B Wright,Jessica Trueman,Kaitlyn Shaw,Michelle Staub,Shahnaz Chaudhry,Fudan Miao, Michelle Higginson,Gabriella S S Groeneweg, James Brown,Laura A Magee,Simon D Whyte,
T. Miyamae, Y. Manabe,T. Sugihara,N. Umezawa,H. Yoshifuji,N. Tamura,Y. Abe, S. Furuta, M. Kato, T. Kumagai, K. Nakamura,H. Nagafuchi,
Annals of the Rheumatic Diseasesno. Suppl 1 (2022): 684-685
Journal of the Canadian Association of Gastroenterologyno. Supplement_1 (2022): 152-153
T. Miyamae, Y. Manabe,T. Sugihara,N. Umezawa,H. Yoshifuji,N. Tamura,Y. Abe, S. Furuta, M. Kato, T. Kumagai, K. Nakamura,H. Nagafuchi,
Cannabis Use in Medicinepp.143-153, (2022)
Load More
Author Statistics
#Papers: 475
#Citation: 11458
H-Index: 53
G-Index: 92
Sociability: 7
Diversity: 1
Activity: 1
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn