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Accurate timing and anticipation of seasonal changes is required to initiate physiological adaptations over the course of the year such as hibernation, changes in metabolism, fattening and reproductive activity. To achieve this, organisms have evolved complex seasonal timekeeping systems that rely on day length sensing (photoperiodism), coupled to innate long-term timers ("circannual clock"). The fundamental biological processes giving rise circannual rhythms are not known for any organism. This is a highly integrative topic of wide relevance, integrating multiple levels of understanding from genome to ecosystem. Within this area, my specific interests are:
- The cellular and molecular mechanisms involved in seasonal timekeeping processes
- The adjustment of homeostatic set points in physiology (rheostasis)
- The function of a specialised cell type in the hypothalamus, the tanycyte, in the above processes
- The use of hibernation and maternal photoperiodic programming to investigate the above processes
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Papers共 44 篇Author StatisticsCo-AuthorSimilar Experts
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crossref(2024)
The Journal of experimental biologyno. 10 (2024)
JOURNAL OF EXPERIMENTAL BIOLOGYno. 23 (2023)
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Proceedings of the National Academy of Sciences of the United States of Americano. 38 (2021)
S H Wood,M M Hindle, Y Mizoro,Y Cheng,B R C Saer,K Miedzinska,H C Christian,N Begley, J McNeilly,A S McNeilly,S L Meddle,D W Burt,
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