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Bio
Dr. Hughes is internationally renowned for his work on the roles of reverse transcriptase (RT) and integrase (IN). He is interested in how HIV becomes resistant to RT and IN inhibitors, in developing drugs that are more effective against the known resistance mutations, and in how the clonal expansion of HIV-infected cells contributes to the formation and persistence of the reservoir that has made it impossible to cure HIV infections with the available drugs. In his role as NIH Scientist Emeritus, Dr. Hughes interacts with scientists inside and outside of the HIV-DRP, providing advice and mentoring.
Research Interests
Papers共 33 篇Author StatisticsCo-AuthorSimilar Experts
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