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RESEARCH
The laboratory is interested in the underlying mechanisms that control the development and function of the immune system. The lab works on two areas:
FoxP3 and the control of CD4+CD25+ regulatory T cell development and function. The forkhead-family transcription factor FoxP3 has been implicated in the development and function of CD4+CD25+ regulatory T cells (Tregs). In the mouse, FoxP3 expression is both necessary and sufficient for generating Tregs, while FoxP3 expression has been shown to correlate with Treg function in humans. My laboratory is taking several approaches to better understand the role of this protein.
The laboratory is interested in the underlying mechanisms that control the development and function of the immune system. The lab works on two areas:
FoxP3 and the control of CD4+CD25+ regulatory T cell development and function. The forkhead-family transcription factor FoxP3 has been implicated in the development and function of CD4+CD25+ regulatory T cells (Tregs). In the mouse, FoxP3 expression is both necessary and sufficient for generating Tregs, while FoxP3 expression has been shown to correlate with Treg function in humans. My laboratory is taking several approaches to better understand the role of this protein.
研究兴趣
论文共 316 篇作者统计合作学者相似作者
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Honyin Chiu, Kristin N Weinstein,Sabine Spath,Alex Hu, Stephanie Varela,Kazushige Obata-Ninomiya,Steven F Ziegler
Journal of immunology (Baltimore, Md. : 1950) (2024)
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYno. 3 (2024): L280-L291
American journal of respiratory and critical care medicineno. 12 (2023): 1565-1575
crossref(2023)
Journal of immunology (Baltimore, Md. : 1950)no. 7 (2023): 888-894
SSRN Electronic Journalno. 79 (2023)
PLOS PATHOGENSno. 11 (2023): e1011350-e1011350
medRxiv : the preprint server for health sciences (2023)
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