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职业迁徙
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Our research focuses on the pathogenesis of tuberculosis with the goal to aid the development of new chemotherapies and vaccines. We investigate the molecular mechanisms that enable Mycobacterium tuberculosis to establish and maintain chronic infections and resist host defenses. We apply molecular genetics to identify new points of vulnerability, which could be targeted to kill populations that escape current chemotherapy in people with latent M. tuberculosis infection. We also analyze host immune factors that are required to control M. tuberculosis and try to identify new strategies to generate improved TB vaccines.
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论文共 176 篇作者统计合作学者相似作者
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biorxiv(2024)
Alexandra H. Miller, Frances Marks, Luming Chan,Helene Botella,Dirk Schnappinger,Sabine Ehrt, Cheryl P. Andam
Microbiology Spectrumno. 7 (2024): e0048724-e0048724
Di Qu, Peng Ge,Laure Botella,Sae Woong Park,Ha-Na Lee, Natalie Thornton,James M Bean,Inna V Krieger,James C Sacchettini,Sabine Ehrt,Courtney C Aldrich,Dirk Schnappinger
Nature communicationsno. 1 (2024): 4161-4161
bioRxiv the preprint server for biology (2023)
JOURNAL OF BIOLOGICAL CHEMISTRYno. 3 (2023): S557-S557
Journal of Biological Chemistryno. 3 (2023): 104034-104034
crossref(2023)
Journal of Immunologyno. 1 (2023): 141.15-141.15
MBio (2023)
bioRxiv : the preprint server for biology (2023)
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