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A fundamental feature of the immune system is the ability to maintain immune homeostasis. Loss of tolerance to self or innocuous foreign antigens can result in autoimmune diseases or transplant rejection, respectively. On the other hand, inappropriate tolerance to antigens such as those present in tumor cells or viruses, can result in loss of tumor immunity or an inability to resolve infectious diseases. Immune responses are tightly regulated at the molecular level, through cellular interactions, and by the microenvironment. Identifying these mechanisms offers the potential to develop more precise immunotherapies for a wide range of dysregulated immune responses. The Crome Lab is focused on delineating regulatory mechanisms which control T cell responses, with a particular focus on innate lymphoid cells and regulatory T cells.
Research Interests
Papers共 56 篇Author StatisticsCo-AuthorSimilar Experts
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Journal of immunology (Baltimore, Md. : 1950)no. 12 (2024): 1904-1912
Carolina de Amat Herbozo, Stephanie WY Wong,Meggie Kuypers, Guy Ilango,Zhewei Liu,Jessica A Mathews,Albert Nguyen,André Veillette,Jennifer L Gommerman, Thomas Baranek,Sarah Q Crome,Ming Sound Tsao,
biorxiv(2024)
AMERICAN JOURNAL OF TRANSPLANTATIONno. 6 (2023): S1067-S1067
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Carolina de Amat Herbozo, Stephanie Wong,Meggie Kuypers, Jessica Matthews,Thomas Baranek,Sarah Crome,Adrian Sacher,Christophe Paget,Thierry Mallevaey
Cancer Immunology Researchno. 12_Supplement (2023)
Frontiers in Immunology (2023): 1275413-1275413
Douglas Chung, Jehan Vakharia,Kathrin Warner,Nicolas Jacquelot,Azin Sayad,SeongJun Han,Maryam Ghaedi,Carlos Garcia-Batres,Alisha R. Elford, Jessica A. Matthews,Ben X. Wang,Linh T. Nguyen,
Journal of Immunologyno. 1 (2023): 172.16-172.16
Journal of the American Society of Nephrologyno. 11S (2023): 588-589
Keith A. Lawson,Shirley Hui,Daniel Stueckmann, Xiaoyu Zhang,Jalna Meens,Lisa Martin,Maria Komisarenko, Julia Szusz,Stephane Chevrier,Sujana Sivapatham,Philip Jonsson,Fred Davis,
CANCER IMMUNOLOGY RESEARCHno. 12 (2023)
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Author Statistics
#Papers: 56
#Citation: 2639
H-Index: 18
G-Index: 30
Sociability: 6
Diversity: 2
Activity: 37
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