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Besides her work on nucleic acid secondary structure prediction, Nussinov is also regarded as a pioneer in DNA sequence analysis for her work in the early 1980s. Nussinov’s algorithm for the prediction of RNA secondary structure is still the leading method. She proposed ‘Conformational Selection and Population Shift’ as an alternative to the textbook ‘Induced-Fit’ model in molecular recognition. Her recent studies unveiled the key role of allostery under normal conditions and in disease and the principles of allosteric drug discovery.
Dr. Nussinov serves as the Editor-in-Chief of PLOS Computational Biology and she is an elected Fellow of the Biophysical Society and the International Society for Computational Biology. She is a Highly Cited Researcher, earning them the mark of exceptional impact.
She also won an award from the AACR in 2017 for her paper on The Key Role of Calmodulin in KRAS-Driven Adenocarcinomas.
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论文共 562 篇作者统计合作学者相似作者
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BIOPHYSICAL JOURNALno. 1 (2024): 57-67
Cell Reportsno. 5 (2024): 114128
JOURNAL OF CHEMICAL INFORMATION AND MODELINGno. 3 (2024): 862-873
Yuan Lin, Theresa A. Ramelot,Simge Senyuz,Attila Gursoy,Hyunbum Jang,Ruth Nussinov, Ozlem Keskin,Yi Zheng
Cancer Researchno. 6_Supplement (2024): 4388-4388
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGYno. 1 (2024): 231-253
Yunguang Qiu,Yuan Hou,Dhruv Gohel, Yadi Zhou,Jielin Xu,Marina Bykova, Yuxin Yang,James B Leverenz,Andrew A Pieper,Ruth Nussinov,Jessica Z K Caldwell,J Mark Brown,
Cell reportsno. 5 (2024): 114128-114128
Cancer Researchno. 7_Supplement (2023): 3845-3845
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Janka Czigleczki, Pedro Tulio de Resende Lara,Balint Dudas,Hyunbum Jang,David Perahia,Ruth Nussinov,Erika Balog
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERSno. SUPPL 1 (2023): S75-S75
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