基本信息
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Bio
Prof. Beyaert’s scientific research is situated at the borderline between molecular biology and medicine, and makes use of a variety of modern biochemical, molecular and cellular approaches combined with mouse gene targeting and mouse models of human inflammatory disease. His most important discoveries include the anti-inflammatory role and mechanism of action of A20 (TNFAIP3), the discovery and characterization of ABIN (TNIP)-1, -2, -3 as ubiquitin-binding proteins and key regulators of inflammation, the development of IL-33 and TSLP cytokine traps, and the discovery of MALT1 protease activity, which have inspired research in many labs worldwide. Their discovery that MALT1 plays a key role in innate and adaptive immune signalling has triggered the development of MALT1 inhibitors by several big pharma companies.
Research Interests
Papers共 544 篇Author StatisticsCo-AuthorSimilar Experts
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FEBS JOURNALno. 6 (2024): 1220-1245
Sudheendra Hebbar Subramanyam, Judit Hriczko,Thomas Look, Tannaz Goodarzi,Tim Clarner,Eva Verjans, Svenja Boell, Christopher Neullens,Ivan Costa, Lin Gan,Bernd Denecke,Angela Schippers,
biorxiv(2024)
biorxiv(2024)
Styliani Iliaki,Marja Kreike, Natalia Ferreras Moreno, Femke De Meyer, Aigerim Aidarova,Harald Braun,Claude Libert,Inna S. Afonina,Rudi Beyaert
Biochemical Pharmacologypp.116316-116316, (2024)
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Aurora Holgado, Zhuangzhuang Liu, Aigerim Aidarova,Christina Mueller,Mira Haegman,Yasmine Driege,Marja Kreike,Charlotte L Scott,Inna S Afonina,Rudi Beyaert
The Journal of allergy and clinical immunologyno. 1 (2023): 244-256.e4
Leonie Wittner, Lukas Wagener,Jakob J Wiese,Iris Stolzer,Susanne M Krug,Elisabeth Naschberger,Rene Jackstadt,Rudi Beyaert,Raja Atreya,Anja A Kühl,Gregor Sturm,Miguel Gonzalez-Acera,
International journal of molecular sciencesno. 8 (2023): 7402-7402
Frontiers in immunology (2023): 1124011-1124011
The FEBS Journal (2023)
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