基本信息
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Bio
We focus on unravelling nature’s complexity to seek for novel drug leads from nature by using integrated chemoinformatic and chemometric approaches. We aim at discovering bioactive compounds from medicinal plants of ethnopharmacological sources (Dioscorides’ de material medica, Chinese herbal medicine) by means of in silico techniques (molecular modelling, virtual screening) and phenotypic screenings using the model organism Caenorhabditis elegans. Our research on bioactive metabolites from diverse natural sources puts special emphasis on natural leads against inflammatory processes, metabolic syndrome, and viral infections/influenza and potential cardiotoxic compounds in commonly consumed botanicals. Moreover, we are also interested in method refinement for analytics and quality control.
Research Interests
Papers共 222 篇Author StatisticsCo-AuthorSimilar Experts
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FRONTIERS IN TOXICOLOGY (2024)
FRONTIERS IN TOXICOLOGY (2024): 1358840-1358840
Andreas Hensel,Rudolf Bauer,Michael Heinrich,Georg Hempel,Olaf Kelber,Karin Kraft, Birka Lehmann, Montserrat Mesegué Medà,Karen Nieber, Bernd Roether,Judith Maria Rollinger, Rüdiger Wiebelitz
Planta medicano. 6 (2024): 416-425
Andreas Hensel,Rudolf Bauer,Michael Heinrich,Georg Hempel,Olaf Kelber,Karin Kraft, Birka Lehmann, Montserrat Mesegué Medà,Karen Nieber, Bernd Roether,Judith Maria Rollinger, Rüdiger Wiebelitz
Planta medica (2024)
Planta medicano. 7-08 (2024): 576-587
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2024): 116010-116010
PLANTA MEDICAno. 14 (2023): 1333-1333
Julia Langeder,Mirijam Koch, Hannes Schmietendorf,Ammar Tahir,Ulrike Grienke,Judith M. Rollinger,Michaela Schmidtke
Frontiers in Pharmacology (2023): 1193118-1193118
Phytochemistry (2023): 113709-113709
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