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Bio
Our lab uses the budding yeast, Saccharomyces cerevisiae to identify mutants and characterize genes affecting structure and function of the nucleus. This includes genes encoding proteins involved in gene regulation, DNA replication or chromatin structure. Current effort is focused on: 1) the mechanism of transcriptional silencing of the mating-type loci (i.e., a study of the yeast equivalent of heterochromatin), 2) identification of genes encoding histone acetyltransferases, deacetylases and other histone modifying enzymes, and 3) the role of the conserved KEOPS complex in tRNA modification and other cellular processes.
Research Interests
Papers共 91 篇Author StatisticsCo-AuthorSimilar Experts
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