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Immunotherapy is making major progress in the clinic and treatment with checkpoint inhibition (CI) results in significant increase in the overall survival among patients with advanced malignant melanoma. Yet, the majority (>50 %) of patients are not helped, why there is a need for improvements by novel combinations and by predictive biomarkers. Administration of tumor infiltrating lymphocytes (TIL) combined with after low dose chemotherapy has been reported to result in long-lasting clinical responses in 20% of the treated patients in patients with metastatic melanoma.
Immunotherapy is making major progress in the clinic and treatment with checkpoint inhibition (CI) results in significant increase in the overall survival among patients with advanced malignant melanoma. Yet, the majority (>50 %) of patients are not helped, why there is a need for improvements by novel combinations and by predictive biomarkers. Administration of tumor infiltrating lymphocytes (TIL) combined with after low dose chemotherapy has been reported to result in long-lasting clinical responses in 20% of the treated patients in patients with metastatic melanoma.
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Shi Yong Neo,Le Tong, Joni Chong, Yaxuan Liu,Xu Jing,Mariana M. S. Oliveira,Yi Chen,Ziqing Chen, Keene Lee, Nutsa Burduli,Xinsong Chen,Juan Gao,
Science Translational Medicineno. 747 (2024)
Shi Yong Neo,Le Tong, Joni Chong, Yaxuan Liu,Xu Jing,Mariana M S Oliveira,Yi Chen,Ziqing Chen, Keene Lee, Nutsa Burduli,Xinsong Chen,Juan Gao,
Science translational medicineno. 747 (2024): eadi2952-eadi2952
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