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Bio
I received training in life sciences in Germany, Australia and USA. As an undergraduate at the German Aerospace Center I studied the effects of space radiation exposure during long-term space missions on the human immune system. Ambitious to learn more about immunology, I conducted my graduate studies at the University of Queensland, Australia. My project was on the generation of regulatory T cells (Treg) in models of autoimmunity. Most Treg fall into a family of T cells that are selected during their development in a special way termed ‘agonist selection’. I became interested in learning more about agonist selected T cells and their role in tolerance as well as mucosal barrier surface protection, and joined Prof. Kristin Hogquist’s group at the University of Minnesota (UMN) as a postdoctoral researcher. There, I studied agonist selected intestinal CD8αα intraepithelial lymphocytes (IEL), and the development of their precursors in the thymus.
In July 2018 I returned to Australia and joined Prof. Alex Loukas' group at the Australian Institute of Tropical Health and Medicine in tropical Queensland, where I continue to work in the field of mucosal immunology with a focus on immune responses to parasitic helminths. These worms were influenced by millions of years of co-evolution with mammalian hosts to efficiently reduce host inflammatory responses in order to avoid expulsion. We study such anti-inflammatory properties and harness them for the development of therapeutics. I am particularly interested in T cell responses to helminths, and how immunity at mucosal surfaces is shaped by molecules secreted by helminths.
Research Interests
Papers共 36 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
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期刊级别
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CANCER RESEARCHno. 6 (2024): 2698-2698
Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)
Science immunologyno. 88 (2023): eadf2163-eadf2163
Journal of Biomolecular Structure and Dynamicspp.1-11, (2023)
Edita Ritmejeryte, Rachael Y. M. Ryan, Brendan Byatt, Yoshimi Peck, Karma Yeshi, Norelle L. Daly, Guangzu Zhao, Darren Crayn, Alex Loukas, Stephen G. Pyne,Roland Ruscher, Phurpa Wangchuk
Frontiers in Parasitology (2022)
Scienceno. 6524 (2021): 22-24
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Author Statistics
#Papers: 35
#Citation: 779
H-Index: 13
G-Index: 23
Sociability: 5
Diversity: 2
Activity: 40
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