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Bio
Dr. Shapiro is an Associate Professor in Medicine at Harvard Medical School and Harvard School of Public Health. He has worked for over two decades in Botswana, performing clinical trials and nationwide surveillance to improve health outcomes for HIV-infected pregnant women and their children. His current research focus is to understand the relationship between antiretroviral drugs used in pregnancy and adverse birth outcomes, and to study novel diagnostic and treatment strategies for HIV-infected children.
In Botswana, Dr. Shapiro has pioneered new strategies to prevent mother-to-child transmission (PMTCT), provided early data to support antiretroviral treatment strategies that were safe enough to allow breastfeeding, and evaluated risks for morbidity and mortality among HIV-exposed infants. He is currently principal investigator or co-principal investigator for research programs that perform: 1) surveillance at 18 sites in Botswana evaluating the relationship between antiretroviral therapy and adverse birth outcomes, including congenital abnormalities; 2) a multi-site study evaluating the safety, efficacy, viral reservoir reduction, and immunologic profiles following very early antiretroviral treatment initiation for HIV-infected infants; and 3) a clinical trial evaluating two broadly neutralizing monoclonal antibodies (bNAbs) as a novel treatment strategy for HIV-infected children. He supports additional research in Botswana as the principal investigator of a Fogarty award, through a successful partnership between Harvard-affiliated hospitals and the Scottish Livingstone Hospital in Botswana, and as a research mentor bridging Boston and Botswana sites. Dr. Shapiro’s research has been used to direct health policy in Botswana and internationally, and through this work he has served as a scientific advisor to the World Health Organization for the development of guidelines for PMTCT, pediatric antiretroviral treatment, and infant feeding.
In Botswana, Dr. Shapiro has pioneered new strategies to prevent mother-to-child transmission (PMTCT), provided early data to support antiretroviral treatment strategies that were safe enough to allow breastfeeding, and evaluated risks for morbidity and mortality among HIV-exposed infants. He is currently principal investigator or co-principal investigator for research programs that perform: 1) surveillance at 18 sites in Botswana evaluating the relationship between antiretroviral therapy and adverse birth outcomes, including congenital abnormalities; 2) a multi-site study evaluating the safety, efficacy, viral reservoir reduction, and immunologic profiles following very early antiretroviral treatment initiation for HIV-infected infants; and 3) a clinical trial evaluating two broadly neutralizing monoclonal antibodies (bNAbs) as a novel treatment strategy for HIV-infected children. He supports additional research in Botswana as the principal investigator of a Fogarty award, through a successful partnership between Harvard-affiliated hospitals and the Scottish Livingstone Hospital in Botswana, and as a research mentor bridging Boston and Botswana sites. Dr. Shapiro’s research has been used to direct health policy in Botswana and internationally, and through this work he has served as a scientific advisor to the World Health Organization for the development of guidelines for PMTCT, pediatric antiretroviral treatment, and infant feeding.
Research Interests
Papers共 205 篇Author StatisticsCo-AuthorSimilar Experts
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The Journal of infectious diseases (2024)
BJOG (2024)
Motswedi Anderson, Thabo Mangogola,Bonolo B. Phinius,Gorata Mpebe,Christopher O. Aimakhu,Wonderful T. Choga,Basetsana Phakedi,Lynnette N. Bhebhe,Doreen Ditshwanelo,Kabo Baruti, Linda Mpofu-Dobo, Lebogang Othusitse,
Microorganismsno. 6 (2024): 1207
American journal of epidemiology (2024)
PloS oneno. 3 (2024): e0299942-e0299942
Rebecca Luckett,Doreen Ramogola-Masire,Devon A. Harris,Annika Gompers, Kelebogile Gaborone, Lorato Mochoba, Lapelo Ntshese,Anikie Mathoma, Maduke Kula,Roger Shapiro,Elysia Larson
Frontiers in global women’s health (2024)
Maureen Sakoi-Mosetlhi, Gbolahan Ajibola, Roxanna Haghighat, Oganne Batlang,Kenneth Maswabi,Molly Pretorius-Holme, Kathleen M Powis,Shahin Lockman,Joseph Makhema, Mathias Litcherfeld,Daniel R Kuritzkes,Roger Shapiro
PloS oneno. 7 (2024): e0307065-e0307065
J. Sroda Agudogo,Maya Jackson-Gibson,Annliz Macharia,Indira Ranaweera, Katlego Boikanyo,Modiegi Diseko,Judith Mabuta, Sarah Hanson, Dudu Rubgega,Bridgette Wamakima,Joseph Makhema,Michele R. Hacker,
American Journal of Obstetrics and Gynecologyno. 1 (2024): S74-S75
Virusesno. 5 (2024): 720-720
Risa M. Hoffman,Sean Brummel,Lauren Ziemba,Lameck Chinula,Katie Mccarthy,Lee Fairlie,Patrick Jean-Philippe,Nahida Chakhtoura, Ben Johnston,Chelsea Krotje,Teacler G. Nematadzira, Frances Nakayiwa,
Clinical infectious diseases : an official publication of the Infectious Diseases Society of Americano. 6 (2024): 1617-1628
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Author Statistics
#Papers: 198
#Citation: 7967
H-Index: 39
G-Index: 87
Sociability: 7
Diversity: 3
Activity: 94
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