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个人简介
Lim is interested in nuclear pore complex (NPC) function and its impact on nucleocytoplasmic transport (NCT) regulation, and how such behavior can be leveraged towards bio-inspired applications. His laboratory combines nanotechnological, biophysical and cellular approaches to unravel the biophysical mechanism(s) that underlie biological NPC function. Their interdisciplinary work has contributed to: (1) resolving the structural dynamics of the NPC selective permeability barrier; (2) understanding NPC transport selectivity and speed on the basis of multivalent Kap-FG Nup binding interactions; and (3) uncovering the role of Kaps in regulating NPC transport function. Subsequently, these insights have provided a fundamental basis for understanding NPC dysfunction, which is closely linked to neurological disease and aging. In the area of nanotechnology, Lim is a co-inventor of ARTIDIS ("Automated and Reliable Tissue Diagnostics"), an atomic force microscope-based innovation that is being commercialized for cancer diagnosis.
研究兴趣
论文共 101 篇作者统计合作学者相似作者
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The Journal of cell biologyno. 2 (2024)
Barak Raveh, Roi Eliasian, Shaked Rashkovits,Daniel Russel,Ryo Hayama,Samuel E Sparks,Digvijay Singh,Roderick Lim,Elizabeth Villa,Michael P Rout,David Cowburn,Andrej Sali
bioRxiv : the preprint server for biology (2024)
Qingzhou Feng, Martin Saladin,Chunxiang Wu, Eason Cao,Wei Zheng, Amy Zhang, Pushpanjali Bhardwaj,Xia Li,Qi Shen,Larisa E Kapinos,Malaiyalam Mariappan,C Patrick Lusk,
bioRxiv : the preprint server for biology (2024)
biorxiv(2023)
Nature Communicationsno. 1 (2023): 1-14
Zenodo (CERN European Organization for Nuclear Research) (2023)
2022 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS)pp.1-2, (2022)
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作者统计
#Papers: 101
#Citation: 4524
H-Index: 35
G-Index: 67
Sociability: 6
Diversity: 0
Activity: 1
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