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个人简介
Bob began his research career while still a resident in psychiatry at Massachusetts Mental Health Center. He worked closely with Dr J Allan Hobson. In 1977 he and Allan published an important paper on the activation-synthesis theory of dreams, which posits that dreams do not have meanings but are the result of the brain’s attempt to make sense of the random firing of neurons. Bob’s research interests were also in studying the brainstem and mechanisms in the brainstem that control REM sleep. He published Brain Control of Wakefulness and Sleep with Dr Mircea M Steriade in 2005. In the previous year, 2004, he published an important paper on adenosine and sleep wakefulness regulation with Drs Radhika Basheer, Robert Strecker, and Mahesh Thakkar.
As a clinically trained and board-certified psychiatrist, he was interested in neuroscience related to schizophrenia, particularly as new technologies made it possible to examine brain physiology and structure in psychiatric populations. This work began in the 1980s with neurophysiology studies of the brain using a form of EEG known as event-related potentials, and with emerging magnetic resonance imaging (MRI) technology to investigate structural abnormalities in patients with schizophrenia. This newer technology, which included the quantitative processing of MR images, was adapted from satellite technology. In 1992 he published a classic paper with Dr Martha Shenton, where they described an important relationship between volume reduction in a brain region involved in thought and language, the left superior temporal gyrus, and a measure of formal thought disorder that reflected disorganized thinking in patients with schizophrenia.
研究兴趣
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BIOLOGICAL PSYCHIATRYno. 9 (2023): S316-S317
Introduction to Psychiatrypp.102-127, (2021)
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#Papers: 987
#Citation: 60108
H-Index: 122
G-Index: 226
Sociability: 8
Diversity: 3
Activity: 26
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