基本信息
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Bio
My personal mission is to apply genetics, genomics and a deep understanding of human biology to improve the lives of patients. For over 20 years, I trained and worked in academic medicine to develop skills in clinical medicine, genetics/genomics and immunology. I came to appreciate the power (and limitations) of these skills in understanding human physiology in health and disease. In 2013, I transitioned to a career in the pharmaceutical industry to apply these skills to discovery and develop transformational medicines via core principles: identifying targets based on causal human biology (including human genetics); recapitulating human biology with appropriate therapeutic modalities; developing robust biomarkers to measure target engagement and modulation; and testing therapeutic hypotheses safely and efficiently in humans. Today, I deploy these principles with an entrepreneurial team at Bristol Myers Squibb (BMS), where I am responsible for two teams: (1) Immunology, Cardiovascular, and Fibrosis Research & Early Development (where we are responsible for the strategic vision, implementation, and partnership of novel therapies for diseases within immunology, cardiovascular, and fibrosis in R&ED), and (2) Translational Medicine (where we are responsible for the translational strategy and execution across our therapeutic areas in late development).
Research Interests
Papers共 236 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
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期刊级别
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Nature reviews. Drug discoverypp.1-1, (2024)
PLoS ONEno. 3 (2019): e0214258
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Author Statistics
#Papers: 236
#Citation: 38207
H-Index: 76
G-Index: 195
Sociability: 8
Diversity: 0
Activity: 0
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