基本信息
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Career Trajectory
Bio
As an Assistant Professor and Swiss Institute of Bioinformatics Group Leader at the Department of Ecology and Evolution of the University of Lausanne since 2017 I am developing the research initiatives of my group with a focus on comparative molecular evolutionary and functional genomics of arthropod biodiversity. My team strives to build bioinformatics tools and resources that facilitate the elucidation of interactions between gene evolution and gene function, developing computational approaches to interrogate evolutionary and functional data: relating gene and genome evolution to gene function, gene expression, and organismal traits.
I am deeply involved in coordinating and leading European efforts for scaling up production of biodiversity genomics data and building data management infrastructures required for efficient processing and open data sharing. My research motivations are on the downstream analyses: data science focused on developing the computational biology tools required to make sense of the molecular data, to characterise how genes and genomes evolve and how this relates to genomic element functions at molecular, cellular, and organismal levels. The biological focus of my group is on arthropods, where rapidly increasing genomic taxonomic sampling combined with their countless evolutionary adaptations mean they are an ideal study system for investigating how conservation or divergence of functional genomic elements give rise to the splendour of animal biology. Our research interfaces evolutionary and computational biology, with a focus on key questions in molecular biology and evolution that are also directly relevant to global public health and with applications to agriculture and the environment in the context of a rapidly changing planet.
Prior to starting my own group, my early postdoctoral research at the University of Geneva focused on comparative genomics where I worked on large-scale orthology delineation (OrthoDB) to investigate principles of molecular evolution and genome biology. During my Marie Curie Fellowship at the Massachusetts Institute of Technology I played a leading role in the sequencing and analysis of multiple mosquito genomes. Returning to Geneva, I helped design and implement the now widely-used software and datasets for assessing genomic data completeness: BUSCO. This focus on computational biology and evolution built on my undergraduate studies in Biochemistry at the University of Oxford and my MSc in Bioinformatics at Imperial College London.
Research Interests
Papers共 127 篇Author StatisticsCo-AuthorSimilar Experts
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期刊级别
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Molecular biology and evolutionno. 3 (2024)
F1000Research (2024)
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MOLECULAR BIOLOGY AND EVOLUTIONno. 3 (2024)
biorxiv(2024)
MOLECULAR ECOLOGY RESOURCESno. 2 (2024)
Nature Biotechnologyno. 3 (2024): 367-370
F1000Research (2024)
PLoS Pathogensno. 3 (2023): e1011257-e1011257
Natureno. 7969 (2023): 252-252
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Author Statistics
#Papers: 127
#Citation: 23615
H-Index: 45
G-Index: 100
Sociability: 8
Diversity: 3
Activity: 38
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