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Bio
Dr Sladek's scientific contributions centre on establishing the role of gene transcription networks in complex traits. He identified key physiological roles for the orphan nuclear receptor ERRalpha in regulating the balance between lipolysis and lipogenesis and ERRbeta in regulating development of the chorion and trophoblast. He has developed methods to identify transcriptional networks de novo in panels of recombinant congenic mouse strains and to characterize transcriptional effects of cis-regulatory genetic variants that underlie complex genetic traits. Most recently, he collaborated with Drs Froguel, Polychronakos, Posner and Prentki to complete the first genome-wide association study (GWAS) to identify risk loci for type 2 diabetes.
Research Interests
Papers共 162 篇Author StatisticsCo-AuthorSimilar Experts
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Soo Heon Kwak, Ryan B Hernandez-Cancela,Daniel A DiCorpo,David E Condon,Jordi Merino,Peitao Wu,Jennifer A Brody,Jie Yao,Xiuqing Guo,Fariba Ahmadizar,Mariah Meyer,Murat Sincan,
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDSno. 3 (2024): 159461-159461
Nanoethicsno. 2 (2024): 9-9
CoRR (2024): 100535
Bioinformaticsno. 5 (2023)
Soo Heon Kwak, Ryan B Hernandez-Cancela,Daniel A DiCorpo,David E Condon,Jordi Merino,Peitao Wu,Jennifer A Brody,Jie Yao,Xiuqing Guo,Fariba Ahmadizar,Mariah Meyer,Murat Sincan,
medRxiv : the preprint server for health sciences (2023)
The Lancet Diabetes & endocrinologyno. 1 (2023): 3-4
Life sciences (2023): 121436-121436
Sara M. Willems,Natasha Hui Jin Ng, Juan Carlos Delgado Fernández,Rebecca S. Fine,Eleanor Wheeler,Jennifer Wessel,Hidetoshi Kitajima,Gaëlle Marenne,Xueling Sim,Hanieh Yaghootkar,Shuai Wang,Sai Chen,
Wellcome open research (2023): 483-483
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Author Statistics
#Papers: 162
#Citation: 19163
H-Index: 46
G-Index: 106
Sociability: 8
Diversity: 3
Activity: 22
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