基本信息
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Career Trajectory
Bio
The Farese-Walther laboratory studies cellular lipid and energy metabolism, in particular the mechanisms and physiology of neutral lipid synthesis and storage in lipid droplets. More broadly, the lab investigates the mechanisms by which cells regulate the abundance of lipids, how they store lipids to buffer fluctuations in their availability, and how these processes function in membrane biology and cell physiology.
Dr. Farese has made important contributions to our understanding of lipid metabolism. His laboratory discovered genes that encode enzymes critical for neutral lipid metabolism, including the DGAT enzymes which mediate triglyceride (TG) synthesis. Excessive accumulation of TGs underlies obesity, diabetes, fatty liver, and other metabolic diseases. Since 2007, Dr. Farese’s laboratory has studied the role of lipid metabolism in the central nervous system, particularly in neurodegenerative disorders such as Frontotemporal Dementia (FTD).
Dr. Farese has made important contributions to our understanding of lipid metabolism. His laboratory discovered genes that encode enzymes critical for neutral lipid metabolism, including the DGAT enzymes which mediate triglyceride (TG) synthesis. Excessive accumulation of TGs underlies obesity, diabetes, fatty liver, and other metabolic diseases. Since 2007, Dr. Farese’s laboratory has studied the role of lipid metabolism in the central nervous system, particularly in neurodegenerative disorders such as Frontotemporal Dementia (FTD).
Research Interests
Papers共 339 篇Author StatisticsCo-AuthorSimilar Experts
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Shubham Singh, Ulrich Dransfeld, Yohannes Ambaw, Joshua Lopez-Scarim,Robert V Farese,Tobias C Walther
bioRxiv : the preprint server for biology (2024)
NATURE CELL BIOLOGYno. 8 (2023): 1085-1086
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Xuewu Sui, Kun Wang,Kangkang Song, Chen Xu,Jiunn Song,Chia-Wei Lee,Maofu Liao,Robert V. Farese,Tobias C. Walther
NATURE COMMUNICATIONSno. 1 (2023): 1-10
Nature communicationsno. 1 (2023)
Chandramohan Chitraju, Alexander W. Fischer,Yohannes A. Ambaw,Kun Wang,Bo Yuan,Sheng Hui,Tobias C. Walther,Robert Farese
eLife (2023)
The FASEB journalno. S1 (2022)
biorxiv(2022)
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Author Statistics
#Papers: 337
#Citation: 38106
H-Index: 94
G-Index: 192
Sociability: 7
Diversity: 0
Activity: 1
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