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The goal of our research is to understand the hierarchical relationship between cells in breast epithelium in order to gain an insight into the processes that underlie cancer initiation in this tissue. The primary aim, therefore, is to characterise and to understand the regulation of mammary epithelial stem cells since these are likely to be the targets of cancer-initiating events, and may be the underlying tumourigenic cells in breast cancers. We also wish to understand how steroid hormones such as oestrogen regulate this cellular hierarchy since both normal and tumour development is hormone dependent.
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Shi-Yang Li, Jan A. Hammarlund,Gang Wu, Jia-Wen Lian,Sacha J. Howell,Robert B. Clarke,Antony D. Adamson,Catia F. Goncalves,John B. Hogenesch,Ron C. Anafi,Qing-Jun Meng
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAno. 7 (2024): e2311854121-e2311854121
Hannah Harrison, Lynsey Rogerson, Hannah J. Gregson,Keith R. Brennan,Robert B. Clarke,Göran Landberg
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CANCER RESEARCHno. 7 (2023)
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Fuhui Chen,Sevim B. Gurler,David Novo,Cigdem Selli,Denis G. Alferez,Secil Eroglu, Kyriaki Pavlou, Jingwei Zhang,Andrew H. Sims,Neil E. Humphreys,Antony Adamson,Andrew Campbell,
Hannah Harrison, Lynsey Rogerson, Hannah J. Gregson,Keith R. Brennan,Robert B. Clarke,Göran Landberg
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Hannah Harrison, Lynsey Rogerson, Hannah J. Gregson,Keith R. Brennan,Robert B. Clarke,Göran Landberg
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