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Adherens junctions (AJs) are specialized intercellular junctions that act as a “molecular glue’’ to bind epithelial cells together to form various tissues in our body. AJs regulate animal development, control tissue homeostasis, and impact human diseases such as cancer. Using Drosophila melanogaster as an in vivo model system, I have studied the assembly and function of AJs to understand the molecular mechanisms by which they regulate cell-cell adhesion and control tissue growth. My expertise is in using the tools of fly genetics, molecular biology, biochemistry, cell biology, and live imaging techniques, to shed light on important fundamental questions in this area.
Adherens junctions (AJs) are specialized intercellular junctions that act as a “molecular glue’’ to bind epithelial cells together to form various tissues in our body. AJs regulate animal development, control tissue homeostasis, and impact human diseases such as cancer. Using Drosophila melanogaster as an in vivo model system, I have studied the assembly and function of AJs to understand the molecular mechanisms by which they regulate cell-cell adhesion and control tissue growth. My expertise is in using the tools of fly genetics, molecular biology, biochemistry, cell biology, and live imaging techniques, to shed light on important fundamental questions in this area.
Research Interests
Papers共 8 篇Author StatisticsCo-AuthorSimilar Experts
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Nature Cell Biologyno. 3 (2013): 261-273
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